node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_1178 | ElbB | DR97_1178 | DR97_2615 | annotation not available | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | 0.572 |
DR97_1178 | gloA | DR97_1178 | DR97_2465 | annotation not available | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione | 0.514 |
DR97_1178 | gloA1 | DR97_1178 | DR97_4418 | annotation not available | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione | 0.509 |
DR97_1178 | gloA2 | DR97_1178 | DR97_1407 | annotation not available | glyox_I: lactoylglutathione lyase | 0.569 |
DR97_1178 | hchA | DR97_1178 | DR97_799 | annotation not available | D-lactate dehydratase / protein deglycase; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and a [...] | 0.581 |
DR97_1178 | nnrD | DR97_1178 | DR97_2302 | annotation not available | Adp-dependent nad(p)h-hydrate dehydratase / nad(p)h-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hyd [...] | 0.626 |
DR97_2614 | ElbB | DR97_2614 | DR97_2615 | Hypothetical protein; Inner membrane protein YohD | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | 0.577 |
DR97_2614 | hemB | DR97_2614 | DR97_2613 | Hypothetical protein; Inner membrane protein YohD | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity) | 0.629 |
DR97_2617 | ElbB | DR97_2617 | DR97_2615 | Hypothetical protein; Uncharacterized protein | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | 0.648 |
ElbB | DR97_1178 | DR97_2615 | DR97_1178 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | annotation not available | 0.572 |
ElbB | DR97_2614 | DR97_2615 | DR97_2614 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | Hypothetical protein; Inner membrane protein YohD | 0.577 |
ElbB | DR97_2617 | DR97_2615 | DR97_2617 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | Hypothetical protein; Uncharacterized protein | 0.648 |
ElbB | gloA | DR97_2615 | DR97_2465 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione | 0.531 |
ElbB | gloA1 | DR97_2615 | DR97_4418 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione | 0.541 |
ElbB | gloA2 | DR97_2615 | DR97_1407 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | glyox_I: lactoylglutathione lyase | 0.705 |
ElbB | hchA | DR97_2615 | DR97_799 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | D-lactate dehydratase / protein deglycase; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and a [...] | 0.736 |
ElbB | hemB | DR97_2615 | DR97_2613 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity) | 0.508 |
ElbB | nnrD | DR97_2615 | DR97_2302 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | Adp-dependent nad(p)h-hydrate dehydratase / nad(p)h-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hyd [...] | 0.566 |
ElbB | surE | DR97_2615 | DR97_4314 | Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate | Stationary phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates | 0.705 |
gloA | DR97_1178 | DR97_2465 | DR97_1178 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione | annotation not available | 0.514 |