| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DR97_4955 | cgtA | DR97_4955 | DR97_1870 | Putative competence protein; comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | 0.534 |
| DR97_4955 | rsmI | DR97_4955 | DR97_1600 | Putative competence protein; comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2 | Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2’-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA | 0.435 |
| DR97_4955 | ysxC | DR97_4955 | DR97_2870 | Putative competence protein; comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2 | Probable GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation | 0.663 |
| cgtA | DR97_4955 | DR97_1870 | DR97_4955 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Putative competence protein; comEC_Rec2- DNA internalization-related competence protein ComEC/Rec2 | 0.534 |
| cgtA | era | DR97_1870 | DR97_1212 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | 0.797 |
| cgtA | ftsY | DR97_1870 | DR97_3340 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components | 0.765 |
| cgtA | rlmB | DR97_1870 | DR97_2287 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | 23S rRNA (guanosine-2’-O-)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA | 0.569 |
| cgtA | rsmH | DR97_1870 | DR97_1598 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.722 |
| cgtA | rsmI | DR97_1870 | DR97_1600 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2’-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA | 0.401 |
| cgtA | ysxC | DR97_1870 | DR97_2870 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | Probable GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation | 0.631 |
| dusB | rlmB | DR97_2203 | DR97_2287 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family | 23S rRNA (guanosine-2’-O-)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA | 0.689 |
| dusB | rsmH | DR97_2203 | DR97_1598 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family | Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.414 |
| dusB | rsmI | DR97_2203 | DR97_1600 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family | Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2’-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA | 0.523 |
| dusB | truA | DR97_2203 | DR97_4819 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs | 0.594 |
| dusB | ysxC | DR97_2203 | DR97_2870 | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family | Probable GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation | 0.741 |
| era | cgtA | DR97_1212 | DR97_1870 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family | 0.797 |
| era | ftsY | DR97_1212 | DR97_3340 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components | 0.400 |
| era | rlmB | DR97_1212 | DR97_2287 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | 23S rRNA (guanosine-2’-O-)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA | 0.484 |
| era | rlmH | DR97_1212 | DR97_3863 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family | 0.540 |
| era | rsmH | DR97_1212 | DR97_1598 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism | Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.662 |
