STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmRGlmR transcriptional regulator; deoR C terminal sensor domain protein (257 aa)    
Predicted Functional Partners:
glmS
Glutamine---fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
  
    0.875
glmU
Bifunctional udp-n-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate n-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain
     
 0.818
fruA
Phosphotransferase system, fructose-specific iibc component; FRU: PTS system, Fru family, IIB component domain protein
 
   
 0.795
FiuR
annotation not available
      
 0.684
FiuI
Rna polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily
      
 0.682
rbsR
annotation not available
  
 
 
 0.648
DR97_2930
annotation not available
       0.638
fruI
Phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family
 
   
 0.631
nagA
Putative n-acetylglucosamine-6-phosphate deacetylase; nagA: N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family
 
   
 0.616
nagE
N-acetylglucosamine pts system eiicba or eiicb component; PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component
 
  
 0.598
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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