node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
csrA | gacA | DR97_1038 | DR97_5459 | A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Probably binds to and is sequestered by non-coding s [...] | Two-component system, narl family, invasion response regulator uvry; Positively controls the production of the autoinducer N- butyryl-homoserine lactone and the formation of the virulence factors pyocyanine, cyanide, and lipase | 0.956 |
csrA | ksgA | DR97_1038 | DR97_3561 | A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Probably binds to and is sequestered by non-coding s [...] | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | 0.764 |
csrA | sun | DR97_1038 | DR97_2970 | A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Probably binds to and is sequestered by non-coding s [...] | Ribosomal rna small subunit methyltransferase b; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA | 0.935 |
fmt | ksgA | DR97_2971 | DR97_3561 | Methionyl-trna formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | 0.505 |
fmt | sun | DR97_2971 | DR97_2970 | Methionyl-trna formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus | Ribosomal rna small subunit methyltransferase b; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA | 0.989 |
fmt | trkA | DR97_2971 | DR97_2969 | Methionyl-trna formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus | annotation not available | 0.887 |
fmt | truB | DR97_2971 | DR97_2085 | Methionyl-trna formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus | Trna pseudouridine(55) synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (By similarity). Osmoprotectant regulator of PLC | 0.549 |
gacA | csrA | DR97_5459 | DR97_1038 | Two-component system, narl family, invasion response regulator uvry; Positively controls the production of the autoinducer N- butyryl-homoserine lactone and the formation of the virulence factors pyocyanine, cyanide, and lipase | A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Probably binds to and is sequestered by non-coding s [...] | 0.956 |
gacA | ksgA | DR97_5459 | DR97_3561 | Two-component system, narl family, invasion response regulator uvry; Positively controls the production of the autoinducer N- butyryl-homoserine lactone and the formation of the virulence factors pyocyanine, cyanide, and lipase | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | 0.685 |
gacA | sun | DR97_5459 | DR97_2970 | Two-component system, narl family, invasion response regulator uvry; Positively controls the production of the autoinducer N- butyryl-homoserine lactone and the formation of the virulence factors pyocyanine, cyanide, and lipase | Ribosomal rna small subunit methyltransferase b; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA | 0.908 |
ksgA | csrA | DR97_3561 | DR97_1038 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Probably binds to and is sequestered by non-coding s [...] | 0.764 |
ksgA | fmt | DR97_3561 | DR97_2971 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | Methionyl-trna formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus | 0.505 |
ksgA | gacA | DR97_3561 | DR97_5459 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | Two-component system, narl family, invasion response regulator uvry; Positively controls the production of the autoinducer N- butyryl-homoserine lactone and the formation of the virulence factors pyocyanine, cyanide, and lipase | 0.685 |
ksgA | rlmE | DR97_3561 | DR97_2096 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | 23S rRNA (uridine2552-2'-O)-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit | 0.918 |
ksgA | rplJ | DR97_3561 | DR97_3639 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | Large subunit ribosomal protein l10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors | 0.955 |
ksgA | rpsA | DR97_3561 | DR97_4774 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | Small subunit ribosomal protein s1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) | 0.978 |
ksgA | sun | DR97_3561 | DR97_2970 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | Ribosomal rna small subunit methyltransferase b; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA | 0.957 |
ksgA | trmB | DR97_3561 | DR97_3349 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | Trna (guanine-n(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA | 0.763 |
ksgA | truB | DR97_3561 | DR97_2085 | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | Trna pseudouridine(55) synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (By similarity). Osmoprotectant regulator of PLC | 0.988 |
rlmE | ksgA | DR97_2096 | DR97_3561 | 23S rRNA (uridine2552-2'-O)-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit | 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | 0.918 |