node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_5944 | pabB | DR97_5944 | DR97_128 | annotation not available | pabB: aminodeoxychorismate synthase, component I | 0.830 |
DR97_5944 | phnA | DR97_5944 | DR97_946 | annotation not available | Anthranilate synthase component i; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, a precursor for Pseudomonas quinolone signal (2-heptyl-3-hydroxy-4-quinolone; PQS) production which is required to induce the genes for the biosynthesis of the virulence factor pyocyanine (PCN), a characteristic blue-green phenazine pigment produced by P.aeruginosa. In the first step, the glutamine-binding beta subunit (PhnB) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with [...] | 0.822 |
DR97_5944 | phzE1 | DR97_5944 | DR97_3697 | annotation not available | annotation not available | 0.999 |
DR97_5944 | trpA | DR97_5944 | DR97_2989 | annotation not available | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate | 0.974 |
DR97_5944 | trpB | DR97_5944 | DR97_2990 | annotation not available | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine | 0.965 |
DR97_5944 | trpC | DR97_5944 | DR97_3604 | annotation not available | indole-3-glycerol phosphate synthase family protein; Belongs to the TrpC family | 0.985 |
DR97_5944 | trpD | DR97_5944 | DR97_3603 | annotation not available | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA) | 0.719 |
DR97_5944 | trpE | DR97_5944 | DR97_3578 | annotation not available | Anthranilate synthase component i; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.822 |
DR97_5944 | trpF | DR97_5944 | DR97_4820 | annotation not available | N-(5'phosphoribosyl)anthranilate (PRA) isomerase family protein; Belongs to the TrpF family | 0.982 |
kynA | trpA | DR97_5590 | DR97_2989 | Putative tryptophan oxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate | 0.943 |
kynA | trpB | DR97_5590 | DR97_2990 | Putative tryptophan oxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine | 0.800 |
pabB | DR97_5944 | DR97_128 | DR97_5944 | pabB: aminodeoxychorismate synthase, component I | annotation not available | 0.830 |
pabB | phnA | DR97_128 | DR97_946 | pabB: aminodeoxychorismate synthase, component I | Anthranilate synthase component i; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, a precursor for Pseudomonas quinolone signal (2-heptyl-3-hydroxy-4-quinolone; PQS) production which is required to induce the genes for the biosynthesis of the virulence factor pyocyanine (PCN), a characteristic blue-green phenazine pigment produced by P.aeruginosa. In the first step, the glutamine-binding beta subunit (PhnB) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with [...] | 0.856 |
pabB | phzE1 | DR97_128 | DR97_3697 | pabB: aminodeoxychorismate synthase, component I | annotation not available | 0.830 |
pabB | trpA | DR97_128 | DR97_2989 | pabB: aminodeoxychorismate synthase, component I | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate | 0.957 |
pabB | trpB | DR97_128 | DR97_2990 | pabB: aminodeoxychorismate synthase, component I | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine | 0.892 |
pabB | trpC | DR97_128 | DR97_3604 | pabB: aminodeoxychorismate synthase, component I | indole-3-glycerol phosphate synthase family protein; Belongs to the TrpC family | 0.967 |
pabB | trpD | DR97_128 | DR97_3603 | pabB: aminodeoxychorismate synthase, component I | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA) | 0.947 |
pabB | trpE | DR97_128 | DR97_3578 | pabB: aminodeoxychorismate synthase, component I | Anthranilate synthase component i; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.836 |
pabB | trpF | DR97_128 | DR97_4820 | pabB: aminodeoxychorismate synthase, component I | N-(5'phosphoribosyl)anthranilate (PRA) isomerase family protein; Belongs to the TrpF family | 0.896 |