node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AcsL | DR97_5615 | DR97_4371 | DR97_5615 | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | annotation not available | 0.918 |
AcsL | acsA1 | DR97_4371 | DR97_1056 | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | Acetyl-coa synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA | 0.920 |
AcsL | acsA2 | DR97_4371 | DR97_2076 | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | Acetyl-coa synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA | 0.917 |
AcsL | bauA | DR97_4371 | DR97_3089 | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | Omega-amino acid--pyruvate aminotransferase; Involved in the degradation of beta-alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L- alanine and 3-oxopropanoate. It can also accept both 4-aminobutyrate and (S)-alpha-methylbenzylamine (MBA) as amino-group donors in the presence of pyruvate as an amine acceptor | 0.860 |
AcsL | bauC | DR97_4371 | DR97_3087 | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase; Involved in the degradation of beta-alanine | 0.926 |
AcsL | bkdB | DR97_4371 | DR97_6301 | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) | 0.912 |
AcsL | mmsB | DR97_4371 | DR97_4370 | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | HIBADH: 3-hydroxyisobutyrate dehydrogenase; Belongs to the 3-hydroxyisobutyrate dehydrogenase family | 0.958 |
AcsL | prpC | DR97_4371 | DR97_1187 | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | 2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family | 0.984 |
AcsL | pta | DR97_4371 | DR97_1109 | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | Phosphate acetyltransferase; Involved in acetate metabolism. In combination with LdhA and AckA, allows fermentation of pyruvate, enhancing long-term survival under anaerobic conditions | 0.959 |
DR97_1241 | bauC | DR97_1241 | DR97_3087 | Putative 3-hydroxyisobutyrate dehydrogenase; NAD-dependent L-serine dehydrogenase that catalyzes the oxidation of L-serine and methyl-L-serine and is possibly involved in serine catabolism. Has low activity toward beta-hydroxyisobutyrate | Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase; Involved in the degradation of beta-alanine | 0.943 |
DR97_1241 | bkdB | DR97_1241 | DR97_6301 | Putative 3-hydroxyisobutyrate dehydrogenase; NAD-dependent L-serine dehydrogenase that catalyzes the oxidation of L-serine and methyl-L-serine and is possibly involved in serine catabolism. Has low activity toward beta-hydroxyisobutyrate | The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) | 0.862 |
DR97_5615 | AcsL | DR97_5615 | DR97_4371 | annotation not available | Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family | 0.918 |
DR97_5615 | acsA1 | DR97_5615 | DR97_1056 | annotation not available | Acetyl-coa synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA | 0.922 |
DR97_5615 | acsA2 | DR97_5615 | DR97_2076 | annotation not available | Acetyl-coa synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA | 0.923 |
DR97_5615 | bauA | DR97_5615 | DR97_3089 | annotation not available | Omega-amino acid--pyruvate aminotransferase; Involved in the degradation of beta-alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L- alanine and 3-oxopropanoate. It can also accept both 4-aminobutyrate and (S)-alpha-methylbenzylamine (MBA) as amino-group donors in the presence of pyruvate as an amine acceptor | 0.810 |
DR97_5615 | bauC | DR97_5615 | DR97_3087 | annotation not available | Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase; Involved in the degradation of beta-alanine | 0.926 |
DR97_5615 | bkdB | DR97_5615 | DR97_6301 | annotation not available | The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) | 0.915 |
DR97_5615 | mmsB | DR97_5615 | DR97_4370 | annotation not available | HIBADH: 3-hydroxyisobutyrate dehydrogenase; Belongs to the 3-hydroxyisobutyrate dehydrogenase family | 0.833 |
DR97_5615 | prpC | DR97_5615 | DR97_1187 | annotation not available | 2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family | 0.954 |
DR97_5615 | pta | DR97_5615 | DR97_1109 | annotation not available | Phosphate acetyltransferase; Involved in acetate metabolism. In combination with LdhA and AckA, allows fermentation of pyruvate, enhancing long-term survival under anaerobic conditions | 0.959 |