node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_2590 | hudA | DR97_2590 | DR97_3211 | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | 0.911 |
DR97_2590 | ubiA | DR97_2590 | DR97_2729 | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate | 0.805 |
DR97_2590 | ubiD | DR97_2590 | DR97_2607 | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis | 0.925 |
DR97_2590 | ubiX | DR97_2590 | DR97_3848 | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | Polyprenyl p-hydroxybenzoate and phenylacrylic acid decarboxylase family protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN | 0.930 |
DR97_3210 | hudA | DR97_3210 | DR97_3211 | annotation not available | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | 0.726 |
PvdI | hudA | DR97_6031 | DR97_3211 | Peptide synthase; D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | 0.698 |
PvdI | ubiD | DR97_6031 | DR97_2607 | Peptide synthase; D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis | 0.698 |
dsbA | hudA | DR97_2867 | DR97_3211 | Protein dithiol oxidoreductase (disulfide-forming); Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins (By similarity) | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | 0.586 |
dsbA | ubiD | DR97_2867 | DR97_2607 | Protein dithiol oxidoreductase (disulfide-forming); Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins (By similarity) | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis | 0.598 |
fabF1 | hudA | DR97_4974 | DR97_3211 | Beta-ketoacyl-acyl-carrier-protein synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | 0.579 |
fabF1 | ubiD | DR97_4974 | DR97_2607 | Beta-ketoacyl-acyl-carrier-protein synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis | 0.579 |
hudA | DR97_2590 | DR97_3211 | DR97_2590 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | 0.911 |
hudA | DR97_3210 | DR97_3211 | DR97_3210 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | annotation not available | 0.726 |
hudA | PvdI | DR97_3211 | DR97_6031 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | Peptide synthase; D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 | 0.698 |
hudA | dsbA | DR97_3211 | DR97_2867 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | Protein dithiol oxidoreductase (disulfide-forming); Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins (By similarity) | 0.586 |
hudA | fabF1 | DR97_3211 | DR97_4974 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | Beta-ketoacyl-acyl-carrier-protein synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP | 0.579 |
hudA | pilF | DR97_3211 | DR97_4064 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | Uncharacterized protein; type_IV_pilW: type IV pilus biogenesis/stability protein PilW | 0.576 |
hudA | slyA | DR97_3211 | DR97_4586 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | annotation not available | 0.747 |
hudA | ubiA | DR97_3211 | DR97_2729 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate | 0.956 |
hudA | ubiD | DR97_3211 | DR97_2607 | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the reversible decarboxylation of aromatic carboxylic acids (Probable). Attenuates the virulence of P.aeruginosa in a Drosophila model when overexpressed | 4-hydroxy-3-polyprenylbenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis | 0.856 |