spuE protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

spuE

Bacterial extracellular solute-binding family protein; Spermidine-binding protein probably required for its uptake into cells. Binds spermidine with high affinity (KD=14.3 nM). Does not bind putrescine, cadaverine or spermine. Spermidine binding induces large inter-domain conformational changes. Implicated in induction of type 3 secretion systems (T3SS), which play a role in virulence (365 aa)

Predicted Functional Partners:

spuG

0.998

spuF

0.997

spuH

0.997

DR97_3176

0.848

potC

0.847

DR97_3288

0.838

DR97_3161

0.834

potB

0.820

DR97_3289

0.810

DR97_3162

0.808

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_3161	DR97_3162	DR97_3161	DR97_3162	annotation not available	annotation not available	0.981
DR97_3161	DR97_3289	DR97_3161	DR97_3289	annotation not available	annotation not available	0.870
DR97_3161	potB	DR97_3161	DR97_4331	annotation not available	annotation not available	0.876
DR97_3161	spuE	DR97_3161	DR97_3263	annotation not available	Bacterial extracellular solute-binding family protein; Spermidine-binding protein probably required for its uptake into cells. Binds spermidine with high affinity (KD=14.3 nM). Does not bind putrescine, cadaverine or spermine. Spermidine binding induces large inter-domain conformational changes. Implicated in induction of type 3 secretion systems (T3SS), which play a role in virulence	0.834
DR97_3161	spuF	DR97_3161	DR97_3264	annotation not available	Polyamine abc transporter, atp-binding family protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system	0.901
DR97_3161	spuG	DR97_3161	DR97_3265	annotation not available	annotation not available	0.958
DR97_3162	DR97_3161	DR97_3162	DR97_3161	annotation not available	annotation not available	0.981
DR97_3162	DR97_3288	DR97_3162	DR97_3288	annotation not available	annotation not available	0.871
DR97_3162	potC	DR97_3162	DR97_4330	annotation not available	annotation not available	0.962
DR97_3162	spuE	DR97_3162	DR97_3263	annotation not available	Bacterial extracellular solute-binding family protein; Spermidine-binding protein probably required for its uptake into cells. Binds spermidine with high affinity (KD=14.3 nM). Does not bind putrescine, cadaverine or spermine. Spermidine binding induces large inter-domain conformational changes. Implicated in induction of type 3 secretion systems (T3SS), which play a role in virulence	0.808
DR97_3162	spuF	DR97_3162	DR97_3264	annotation not available	Polyamine abc transporter, atp-binding family protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system	0.896
DR97_3162	spuH	DR97_3162	DR97_3266	annotation not available	annotation not available	0.956
DR97_3176	spuE	DR97_3176	DR97_3263	4-(gamma-glutamylamino)butanal dehydrogenase; Belongs to the aldehyde dehydrogenase family	Bacterial extracellular solute-binding family protein; Spermidine-binding protein probably required for its uptake into cells. Binds spermidine with high affinity (KD=14.3 nM). Does not bind putrescine, cadaverine or spermine. Spermidine binding induces large inter-domain conformational changes. Implicated in induction of type 3 secretion systems (T3SS), which play a role in virulence	0.848
DR97_3288	DR97_3162	DR97_3288	DR97_3162	annotation not available	annotation not available	0.871
DR97_3288	DR97_3289	DR97_3288	DR97_3289	annotation not available	annotation not available	0.997
DR97_3288	potB	DR97_3288	DR97_4331	annotation not available	annotation not available	0.974
DR97_3288	potC	DR97_3288	DR97_4330	annotation not available	annotation not available	0.819
DR97_3288	spuE	DR97_3288	DR97_3263	annotation not available	Bacterial extracellular solute-binding family protein; Spermidine-binding protein probably required for its uptake into cells. Binds spermidine with high affinity (KD=14.3 nM). Does not bind putrescine, cadaverine or spermine. Spermidine binding induces large inter-domain conformational changes. Implicated in induction of type 3 secretion systems (T3SS), which play a role in virulence	0.838
DR97_3288	spuF	DR97_3288	DR97_3264	annotation not available	Polyamine abc transporter, atp-binding family protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system	0.900
DR97_3288	spuG	DR97_3288	DR97_3265	annotation not available	annotation not available	0.868

page 1 of 4

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2021

Credits

Access

Info

About