node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_223 | sbcD | DR97_223 | DR97_1456 | annotation not available | Dna repair protein sbcd/mre11; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity | 0.688 |
DR97_223 | serA | DR97_223 | DR97_3280 | annotation not available | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | 0.649 |
DR97_3281 | serA | DR97_3281 | DR97_3280 | annotation not available | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | 0.644 |
DR97_3389 | serA | DR97_3389 | DR97_3280 | annotation not available | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | 0.749 |
cysM | serA | DR97_1007 | DR97_3280 | S-sulfo-l-cysteine synthase (o-acetyl-l-serine-dependent); cysM: cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | 0.659 |
cysM | serC | DR97_1007 | DR97_4769 | S-sulfo-l-cysteine synthase (o-acetyl-l-serine-dependent); cysM: cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine | 0.613 |
gpmI | serA | DR97_2485 | DR97_3280 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | 0.918 |
gyrB | serA | DR97_2953 | DR97_3280 | Dna gyrase, b subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | 0.649 |
gyrB | truA | DR97_2953 | DR97_4819 | Dna gyrase, b subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | Trna pseudouridine(38-40) synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs | 0.678 |
sbcD | DR97_223 | DR97_1456 | DR97_223 | Dna repair protein sbcd/mre11; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity | annotation not available | 0.688 |
sbcD | serA | DR97_1456 | DR97_3280 | Dna repair protein sbcd/mre11; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | 0.652 |
serA | DR97_223 | DR97_3280 | DR97_223 | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | annotation not available | 0.649 |
serA | DR97_3281 | DR97_3280 | DR97_3281 | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | annotation not available | 0.644 |
serA | DR97_3389 | DR97_3280 | DR97_3389 | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | annotation not available | 0.749 |
serA | cysM | DR97_3280 | DR97_1007 | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | S-sulfo-l-cysteine synthase (o-acetyl-l-serine-dependent); cysM: cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family | 0.659 |
serA | gpmI | DR97_3280 | DR97_2485 | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate | 0.918 |
serA | gyrB | DR97_3280 | DR97_2953 | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | Dna gyrase, b subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | 0.649 |
serA | sbcD | DR97_3280 | DR97_1456 | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | Dna repair protein sbcd/mre11; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity | 0.652 |
serA | serC | DR97_3280 | DR97_4769 | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine | 0.993 |
serA | trpB | DR97_3280 | DR97_2990 | D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine | 0.707 |