STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR97_3292Uncharacterized protein; Autotrans_barl: outer membrane autotransporter barrel domain protein (647 aa)    
Predicted Functional Partners:
DR97_3268
Hypothetical protein; Transcriptional regulator
  
     0.564
pfeA
Tonb-dependent siderophore receptor family protein; Specific receptor for the siderophore ferric enterobactin
  
     0.537
DR97_3081
annotation not available
  
     0.530
HxuC
Heme utilization protein; tonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein
  
    0.526
DR97_3726
annotation not available
  
     0.518
cupA4
annotation not available
  
  
 0.512
DR97_3082
annotation not available
  
     0.510
YybH
Hypothetical protein; Uncharacterized protein
  
    0.478
DR97_5207
Hypothetical protein; Uncharacterized protein
  
     0.472
pprA
Putative two-component sensor; Member of the two-component regulatory system PprA/PprB involved in biofilm formation by controlling the expression of many related genes including type IVb pili major subunit flp pilin, adhesin bapA or cupE fimbriae Modulates also quorum-sensing signal production acting on both negative and positive modulators . Functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to PprB
  
     0.452
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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