STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metCannotation not available (394 aa)    
Predicted Functional Partners:
DR97_3367
annotation not available
 0.999
metH
Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity)
  
 
 0.985
metE
Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
  
 
 0.982
cysK
Belongs to the cysteine synthase/cystathionine beta- synthase family
 0.975
sseA
Transfers a sulfur ion to cyanide or to other thiol compounds
 
 
 0.972
DR97_882
annotation not available
 0.949
ilvE
Acts on leucine, isoleucine and valine
  
 0.933
hom
annotation not available
  
 
 0.923
metF
Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.922
rhdA
Catalyzes the sulfur transfer reaction from thiosulfate to cyanide, thus converting cyanide to the less toxic thiocyanate . Contributes to P.aeruginosa survival under cyanogenic conditions, and thus provides the bacterium with a defense mechanism against endogenous cyanide toxicity . Is the main cytoplasmic rhodanese in P.aeruginosa, accounting for 90% of total rhodanese activity
 
 
 0.921
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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