pyrR protein (Pseudomonas aeruginosa) - STRING interaction network

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pyrR

Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (170 aa)

Predicted Functional Partners:

pyrB

0.996

pyrC'

0.974

pyrF

0.967

upp

0.935

preA

0.925

mazG

0.914

surE

0.911

pyrH

0.908

DR97_3408

0.902

ppnP

0.900

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_3408	ppnP	DR97_3408	DR97_361	annotation not available	Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	0.900
DR97_3408	preA	DR97_3408	DR97_3407	annotation not available	NAD-dependent dihydropyrimidine dehydrogenase subunit PreA; pyrD_sub1_fam- dihydroorotate dehydrogenase family domain protein	0.999
DR97_3408	pyrC'	DR97_3408	DR97_3369	annotation not available	Multifunctional complex type domain protein; pyrC_multi- dihydroorotase, multifunctional complex type domain protein	0.490
DR97_3408	pyrR	DR97_3408	DR97_3371	annotation not available	Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	0.902
DR97_3408	upp	DR97_3408	DR97_1955	annotation not available	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	0.900
mazG	pyrF	DR97_1004	DR97_5065	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	Orotidine 5’-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5’- monophosphate (OMP) to uridine 5’-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily	0.905
mazG	pyrH	DR97_1004	DR97_4285	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP	0.900
mazG	pyrR	DR97_1004	DR97_3371	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	0.914
mazG	surE	DR97_1004	DR97_4314	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family	0.904
mazG	upp	DR97_1004	DR97_1955	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	0.904
ppnP	DR97_3408	DR97_361	DR97_3408	Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	annotation not available	0.900
ppnP	preA	DR97_361	DR97_3407	Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	NAD-dependent dihydropyrimidine dehydrogenase subunit PreA; pyrD_sub1_fam- dihydroorotate dehydrogenase family domain protein	0.900
ppnP	pyrR	DR97_361	DR97_3371	Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	0.900
ppnP	surE	DR97_361	DR97_4314	Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family	0.900
ppnP	upp	DR97_361	DR97_1955	Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	0.904
preA	DR97_3408	DR97_3407	DR97_3408	NAD-dependent dihydropyrimidine dehydrogenase subunit PreA; pyrD_sub1_fam- dihydroorotate dehydrogenase family domain protein	annotation not available	0.999
preA	ppnP	DR97_3407	DR97_361	NAD-dependent dihydropyrimidine dehydrogenase subunit PreA; pyrD_sub1_fam- dihydroorotate dehydrogenase family domain protein	Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	0.900
preA	pyrC'	DR97_3407	DR97_3369	NAD-dependent dihydropyrimidine dehydrogenase subunit PreA; pyrD_sub1_fam- dihydroorotate dehydrogenase family domain protein	Multifunctional complex type domain protein; pyrC_multi- dihydroorotase, multifunctional complex type domain protein	0.581
preA	pyrF	DR97_3407	DR97_5065	NAD-dependent dihydropyrimidine dehydrogenase subunit PreA; pyrD_sub1_fam- dihydroorotate dehydrogenase family domain protein	Orotidine 5’-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5’- monophosphate (OMP) to uridine 5’-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily	0.444
preA	pyrR	DR97_3407	DR97_3371	NAD-dependent dihydropyrimidine dehydrogenase subunit PreA; pyrD_sub1_fam- dihydroorotate dehydrogenase family domain protein	Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	0.925

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