Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| YqgF | algH | DR97_3372 | DR97_3373 | Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | 0.970 |
| YqgF | tonB3 | DR97_3372 | DR97_3374 | Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA | Tonb domain-containing protein; tonB_Cterm: TonB family C-terminal domain protein | 0.789 |
| algH | YqgF | DR97_3373 | DR97_3372 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA | 0.970 |
| algH | algQ | DR97_3373 | DR97_2626 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | Regulator of rna polymerase sigma(70) subunit, rsd/algq family protein; The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i.e. under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process | 0.852 |
| algH | dnaN | DR97_3373 | DR97_2951 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | 0.911 |
| algH | dut | DR97_3373 | DR97_2692 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | 0.877 |
| algH | nrdA | DR97_3373 | DR97_778 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides | 0.949 |
| algH | nrdJa | DR97_3373 | DR97_2875 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | 0.949 |
| algH | nrdJb | DR97_3373 | DR97_2874 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | annotation not available | 0.949 |
| algH | polA | DR97_3373 | DR97_2871 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity | 0.775 |
| algH | thyA | DR97_3373 | DR97_3308 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis | 0.869 |
| algH | tonB3 | DR97_3373 | DR97_3374 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | Tonb domain-containing protein; tonB_Cterm: TonB family C-terminal domain protein | 0.784 |
| algQ | algH | DR97_2626 | DR97_3373 | Regulator of rna polymerase sigma(70) subunit, rsd/algq family protein; The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i.e. under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | 0.852 |
| dnaN | algH | DR97_2951 | DR97_3373 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family | 0.911 |
| dnaN | dut | DR97_2951 | DR97_2692 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | 0.913 |
| dnaN | nrdA | DR97_2951 | DR97_778 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides | 0.800 |
| dnaN | nrdJa | DR97_2951 | DR97_2875 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | 0.773 |
| dnaN | nrdJb | DR97_2951 | DR97_2874 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | annotation not available | 0.773 |
| dnaN | polA | DR97_2951 | DR97_2871 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity | 0.999 |
| dnaN | thyA | DR97_2951 | DR97_3308 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for proces [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis | 0.877 |
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