STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR97_3416annotation not available (540 aa)    
Predicted Functional Partners:
glpT
Mfs transporter, opa family, glycerol-3-phosphate transporter; glpT: glycerol-3-phosphate transporter
   
  
 0.865
DR97_1429
annotation not available
     
 0.863
phoA2
Alkaline phosphatase l; Has both a phosphomonoesterase and phosphodiesterase activity
     
 0.863
pstS
Phosphate transport system substrate-binding protein; Binds 1 inorganic phosphate per subunit with a KD of 0.34 uM . Required for phosphate transport . In strain PAO1 implicated in host cell adhesion; in some virulent strains (e.g. MDR25 which expresses very high levels of this protein) antibody fragments against this protein decrease host cell adhesion and increase transepithelial resistance of human epithelial cell monolayers. Its ability to bind phosphate may allow it to acquire phosphate from its host
     
 0.862
pstA
3a0107s02c: phosphate ABC transporter, permease protein PstA
     
 0.748
phoR
Two-component system, ompr family, phosphate regulon sensor histidine kinase phor; Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals
     
 0.576
ppx
Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain . Has also polyphosphate:ADP phosphotransferase activity, catalyzing the production of ATP from ADP and polyP
     
 0.574
cysN/C
Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity
     
 0.558
YajR
annotation not available
  
  
 0.528
ppk1
Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
     
 0.525
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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