STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR97_3425Drug resistance mfs transporter, drug:h+ antiporter-2 family protein; Belongs to the major facilitator superfamily (477 aa)    
Predicted Functional Partners:
DR97_3423
Hypothetical protein; Uncharacterized protein
       0.845
plcR
Phospholipase c accessory protein plcr; May be involved in the regulation of synthesis of phospholipase C
      
 0.682
pepN
pepN_proteo: aminopeptidase N
   
  0.576
DR97_5643
Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
  
 
 0.509
ruvC
Crossover junction endodeoxyribonuclease ruvc; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
   
 
 0.505
EmrA
Membrane fusion protein, multidrug efflux system; Multidrug resistance protein A; RND_mfp: efflux transporter, RND family, MFP subunit
 
 
 
 0.471
DR97_588
Putative rnd efflux membrane fusion protein precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
 
 
 0.469
DR97_2361
annotation not available
   
  0.438
DR97_697
Membrane fusion protein, multidrug efflux system; Putative multidrug resistance efflux pump; RND_mfp: efflux transporter, RND family, MFP subunit
 
 
 
 0.424
TrpB
Membrane fusion protein, multidrug efflux system; Secretion protein; RND_mfp: efflux transporter, RND family, MFP subunit
 
 
 
 0.409
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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