STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
NorDVon willebrand factor type a domain protein; Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). Function unknown, but essential for the denitrification process (612 aa)    
Predicted Functional Partners:
norB
Nitric oxide reductase subunit b; Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorB is the catalytic subunit of the enzyme complex. Shows proton pump activity across the membrane in denitrifying bacterial cells. The mononitrogen reduction is probably coupled to electron transport phosphorylation (By similarity)
 
  
 0.993
nirQ
Nitric oxide reductase norq protein; Activator of nitrite and nitric oxide reductases
 
  
 0.984
norC
Nitric-oxide reductase subunit c; Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification)
 
  
 0.976
NirO
annotation not available
 
  
 0.946
nosD
Copper abc transporter periplasmic substrate-binding protein; Required for the assembly of the copper chromophores of nitrous oxide reductase. Could be part of the ABC transporter complex NosDFY
 
  
 0.905
nirS
annotation not available
 
  
 0.896
nosR
Nosr/niri family transcriptional regulator, nitrous oxide reductase regulator; Transcriptional activator of the nitrous-oxide reductase gene NosZ
 
  
 0.877
nosZ
Nitrous-oxide reductase, tat-dependent; Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide
 
  
 0.862
nirC
Cytochrome c oxidase, cbb3-type, subunit iii family protein; Monoheme c-type cytochrome
 
  
 0.858
nirN
annotation not available
 
  
 0.823
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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