node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ahcY | metE | DR97_3400 | DR97_5918 | S-adenosyl-l-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation | 0.996 |
ahcY | metH | DR97_3400 | DR97_34 | S-adenosyl-l-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity) | 0.985 |
ahcY | metK | DR97_3400 | DR97_3515 | S-adenosyl-l-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme | 0.990 |
aspC | metE | DR97_4790 | DR97_5918 | Aminotransferase class i and ii family protein; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation | 0.911 |
aspC | metH | DR97_4790 | DR97_34 | Aminotransferase class i and ii family protein; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity) | 0.922 |
aspC | metK | DR97_4790 | DR97_3515 | Aminotransferase class i and ii family protein; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme | 0.911 |
aspC | phhC | DR97_4790 | DR97_1073 | Aminotransferase class i and ii family protein; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Aminotransferase class i and ii family protein; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 0.822 |
aspC | tpiA | DR97_4790 | DR97_2092 | Aminotransferase class i and ii family protein; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Triosephosphate isomerase (tim); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P) | 0.589 |
lasI | metK | DR97_591 | DR97_3515 | Acyl homoserine lactone synthase; Required for the synthesis of PAI consisting of 3-oxo-N- (tetrahydro-2-oxo-3-furanyl)-dodecanamide also known as N-(3- oxododecanoyl)homoserine lactone, an autoinducer molecule which binds to LasR and thus acts in elastase biosynthesis regulation | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme | 0.906 |
lasI | rhlI | DR97_591 | DR97_4445 | Acyl homoserine lactone synthase; Required for the synthesis of PAI consisting of 3-oxo-N- (tetrahydro-2-oxo-3-furanyl)-dodecanamide also known as N-(3- oxododecanoyl)homoserine lactone, an autoinducer molecule which binds to LasR and thus acts in elastase biosynthesis regulation | Autoinducer synthetase family protein; Required for the synthesis of BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone) autoinducer molecules which bind to RhlR and thus acts in elastase biosynthesis regulation | 0.891 |
lasI | speD | DR97_591 | DR97_3607 | Acyl homoserine lactone synthase; Required for the synthesis of PAI consisting of 3-oxo-N- (tetrahydro-2-oxo-3-furanyl)-dodecanamide also known as N-(3- oxododecanoyl)homoserine lactone, an autoinducer molecule which binds to LasR and thus acts in elastase biosynthesis regulation | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine | 0.901 |
lasI | speH | DR97_591 | DR97_2117 | Acyl homoserine lactone synthase; Required for the synthesis of PAI consisting of 3-oxo-N- (tetrahydro-2-oxo-3-furanyl)-dodecanamide also known as N-(3- oxododecanoyl)homoserine lactone, an autoinducer molecule which binds to LasR and thus acts in elastase biosynthesis regulation | Putative s-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine | 0.900 |
metE | ahcY | DR97_5918 | DR97_3400 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation | S-adenosyl-l-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine | 0.996 |
metE | aspC | DR97_5918 | DR97_4790 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation | Aminotransferase class i and ii family protein; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 0.911 |
metE | metH | DR97_5918 | DR97_34 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity) | 0.988 |
metE | metK | DR97_5918 | DR97_3515 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme | 0.997 |
metE | phhC | DR97_5918 | DR97_1073 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation | Aminotransferase class i and ii family protein; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 0.911 |
metH | ahcY | DR97_34 | DR97_3400 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity) | S-adenosyl-l-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine | 0.985 |
metH | aspC | DR97_34 | DR97_4790 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity) | Aminotransferase class i and ii family protein; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 0.922 |
metH | metE | DR97_34 | DR97_5918 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity) | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation | 0.988 |