STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR97_3764Hdig domain-containing protein; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP . Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture (414 aa)    
Predicted Functional Partners:
DR97_5603
annotation not available
 
 0.775
DR97_5178
GGDEF: diguanylate cyclase domain protein
 
 0.694
DR97_830
GGDEF: diguanylate cyclase domain protein
 
 0.661
DR97_3759
annotation not available
 
   
 0.637
DR97_4677
Putative EAL domain/GGDEF domain-containing protein; GGDEF: diguanylate cyclase domain protein
 
 
 
 0.637
DR97_3252
Sensory box ggdef domain-containing protein; GGDEF: diguanylate cyclase domain protein
 
 0.628
DR97_4759
Sensory box ggdef domain-containing protein; GGDEF: diguanylate cyclase domain protein
 
 
 0.625
DR97_4616
Putative signaling protein PA3311; GGDEF: diguanylate cyclase domain protein
  
 0.586
fimX
GGDEF: diguanylate cyclase domain protein
 
 
 
 0.557
DR97_2372
Cyclic di-GMP phosphodiesterase Gmr; GGDEF: diguanylate cyclase domain protein
 
 
 0.555
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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