node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_1650 | DR97_3777 | DR97_1650 | DR97_3777 | annotation not available | Uncharacterized protein; DUF2218 domain-containing protein | 0.420 |
DR97_3196 | DR97_3777 | DR97_3196 | DR97_3777 | annotation not available | Uncharacterized protein; DUF2218 domain-containing protein | 0.711 |
DR97_3777 | DR97_1650 | DR97_3777 | DR97_1650 | Uncharacterized protein; DUF2218 domain-containing protein | annotation not available | 0.420 |
DR97_3777 | DR97_3196 | DR97_3777 | DR97_3196 | Uncharacterized protein; DUF2218 domain-containing protein | annotation not available | 0.711 |
DR97_3777 | DR97_3778 | DR97_3777 | DR97_3778 | Uncharacterized protein; DUF2218 domain-containing protein | annotation not available | 0.460 |
DR97_3777 | DR97_3779 | DR97_3777 | DR97_3779 | Uncharacterized protein; DUF2218 domain-containing protein | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | 0.525 |
DR97_3777 | hpaB | DR97_3777 | DR97_3776 | Uncharacterized protein; DUF2218 domain-containing protein | 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN . In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde | 0.496 |
DR97_3777 | hpaC | DR97_3777 | DR97_3775 | Uncharacterized protein; DUF2218 domain-containing protein | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Reductase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the reduction of FAD by NADH. The reduced flavin is then transferred to the oxygenase component HpaB. Is also able to reduce FMN and riboflavin, but preferentially binds FAD. Has no activity with NADPH as the reductant | 0.449 |
DR97_3777 | moaF | DR97_3777 | DR97_3780 | Uncharacterized protein; DUF2218 domain-containing protein | annotation not available | 0.460 |
DR97_3778 | DR97_3777 | DR97_3778 | DR97_3777 | annotation not available | Uncharacterized protein; DUF2218 domain-containing protein | 0.460 |
DR97_3778 | DR97_3779 | DR97_3778 | DR97_3779 | annotation not available | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | 0.901 |
DR97_3778 | moaF | DR97_3778 | DR97_3780 | annotation not available | annotation not available | 0.932 |
DR97_3779 | DR97_3777 | DR97_3779 | DR97_3777 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | Uncharacterized protein; DUF2218 domain-containing protein | 0.525 |
DR97_3779 | DR97_3778 | DR97_3779 | DR97_3778 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | annotation not available | 0.901 |
DR97_3779 | hpaB | DR97_3779 | DR97_3776 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN . In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde | 0.507 |
DR97_3779 | moaF | DR97_3779 | DR97_3780 | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | annotation not available | 0.884 |
hpaB | DR97_3777 | DR97_3776 | DR97_3777 | 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN . In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde | Uncharacterized protein; DUF2218 domain-containing protein | 0.496 |
hpaB | DR97_3779 | DR97_3776 | DR97_3779 | 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN . In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde | Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family | 0.507 |
hpaB | hpaC | DR97_3776 | DR97_3775 | 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN . In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde | 4-hydroxyphenylacetate 3-monooxygenase, reductase component; Reductase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the reduction of FAD by NADH. The reduced flavin is then transferred to the oxygenase component HpaB. Is also able to reduce FMN and riboflavin, but preferentially binds FAD. Has no activity with NADPH as the reductant | 0.998 |
hpaB | moaF | DR97_3776 | DR97_3780 | 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN . In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde | annotation not available | 0.630 |