node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adk | rsgA | DR97_4191 | DR97_2305 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism | Ribosome biogenesis gtpase / thiamine phosphate phosphatase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit | 0.915 |
adk | thiL | DR97_4191 | DR97_3816 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 | 0.902 |
nusB | pgpA | DR97_3815 | DR97_3817 | Transcription antitermination protein nusb; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons | Phosphatidylglycerophosphatase a family protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) | 0.889 |
nusB | ribB | DR97_3815 | DR97_3813 | Transcription antitermination protein nusb; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | 0.932 |
nusB | ribH | DR97_3815 | DR97_3814 | Transcription antitermination protein nusb; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | 0.997 |
nusB | thiL | DR97_3815 | DR97_3816 | Transcription antitermination protein nusb; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 | 0.965 |
pgpA | nusB | DR97_3817 | DR97_3815 | Phosphatidylglycerophosphatase a family protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) | Transcription antitermination protein nusb; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons | 0.889 |
pgpA | ribB | DR97_3817 | DR97_3813 | Phosphatidylglycerophosphatase a family protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | 0.813 |
pgpA | ribH | DR97_3817 | DR97_3814 | Phosphatidylglycerophosphatase a family protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | 0.886 |
pgpA | thiL | DR97_3817 | DR97_3816 | Phosphatidylglycerophosphatase a family protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 | 0.919 |
phoA | rsgA | DR97_4634 | DR97_2305 | Alkaline phosphatase h; Has only phosphomonoesterase activity | Ribosome biogenesis gtpase / thiamine phosphate phosphatase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit | 0.800 |
phoA | thiE | DR97_4634 | DR97_3889 | Alkaline phosphatase h; Has only phosphomonoesterase activity | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) | 0.903 |
phoA | thiL | DR97_4634 | DR97_3816 | Alkaline phosphatase h; Has only phosphomonoesterase activity | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 | 0.906 |
ribB | nusB | DR97_3813 | DR97_3815 | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | Transcription antitermination protein nusb; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons | 0.932 |
ribB | pgpA | DR97_3813 | DR97_3817 | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | Phosphatidylglycerophosphatase a family protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) | 0.813 |
ribB | ribH | DR97_3813 | DR97_3814 | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | 0.999 |
ribB | rsgA | DR97_3813 | DR97_2305 | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | Ribosome biogenesis gtpase / thiamine phosphate phosphatase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit | 0.512 |
ribB | thiD | DR97_3813 | DR97_3890 | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | annotation not available | 0.657 |
ribB | thiE | DR97_3813 | DR97_3889 | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) | 0.533 |
ribB | thiL | DR97_3813 | DR97_3816 | Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase ii protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 | 0.922 |