STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR97_3867Rare lipoa family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides (342 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall
 
 
 0.990
sltB1
mltB: lytic murein transglycosylase B
  
  
 0.988
mrdB
Rod shape determining protein roda; Peptidoglycan polymerase that is essential for cell wall elongation
 
 
 0.986
safA
Membrane-bound lytic murein transglycosylase D; spore_safA: spore coat assembly SafA domain protein
  
 
 0.979
dacC
Serine-type d-ala-d-ala carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family
  
  
 0.972
mltG
Yceg-like family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
  
   
 0.947
NlpD
annotation not available
 
 
 0.944
MltA
Putative membrane-bound lytic murein transglycosylase a; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division
   
  
 0.928
mltF
Bacterial extracellular solute-binding s, 3 family protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella
   
  
 0.897
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate
  
  
 0.893
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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