STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacCSerine-type d-ala-d-ala carboxypeptidase (penicillin-binding protein 5/6); Belongs to the peptidase S11 family (386 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall
 
 
 0.994
mrcA
Penicillin-binding , 1a family protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits)
     
 0.983
dacB
Serine-type d-ala-d-ala carboxypeptidase/endopeptidase (penicillin-binding protein 4); PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase
    
 0.979
mrdB
Rod shape determining protein roda; Peptidoglycan polymerase that is essential for cell wall elongation
 
 
 0.973
DR97_3867
Rare lipoa family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
  
  
 0.972
rlpA
Rare lipoa family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
  
  
 0.881
sltB1
mltB: lytic murein transglycosylase B
 
   
 0.872
ftsI
Cell division protein ftsi (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin
 
 
 0.790
pbpC
Cell division protein ftsi (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin
 
 
 0.790
DR97_3884
annotation not available
      0.775
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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