thiD protein (Pseudomonas aeruginosa) - STRING interaction network

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Score

thiD

annotation not available (265 aa)

Predicted Functional Partners:

thiE

0.999

thiC

0.999

thiG

0.956

thiL

0.884

ribD

0.854

thiI

0.839

hemL

0.828

moeB

0.736

guaA

0.726

purL

0.658

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
guaA	purL	DR97_4101	DR97_4112	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	0.988
guaA	ribD	DR97_4101	DR97_3811	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.692
guaA	thiD	DR97_4101	DR97_3890	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	annotation not available	0.726
guaA	thiG	DR97_4101	DR97_3348	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	0.644
guaA	thiI	DR97_4101	DR97_2472	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	0.598
hemL	ribD	DR97_3888	DR97_3811	hemL- glutamate-1-semialdehyde-2,1-aminomutase	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.583
hemL	thiD	DR97_3888	DR97_3890	hemL- glutamate-1-semialdehyde-2,1-aminomutase	annotation not available	0.828
hemL	thiE	DR97_3888	DR97_3889	hemL- glutamate-1-semialdehyde-2,1-aminomutase	thiE- thiamine-phosphate pyrophosphorylase	0.934
moeB	ribD	DR97_1972	DR97_3811	annotation not available	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.573
moeB	thiC	DR97_1972	DR97_2326	annotation not available	Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	0.758
moeB	thiD	DR97_1972	DR97_3890	annotation not available	annotation not available	0.736
moeB	thiE	DR97_1972	DR97_3889	annotation not available	thiE- thiamine-phosphate pyrophosphorylase	0.687
moeB	thiG	DR97_1972	DR97_3348	annotation not available	Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	0.874
moeB	thiI	DR97_1972	DR97_2472	annotation not available	tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	0.933
moeB	thiL	DR97_1972	DR97_3816	annotation not available	Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family	0.403
purL	guaA	DR97_4112	DR97_4101	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.988
purL	thiD	DR97_4112	DR97_3890	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	annotation not available	0.658
purL	thiE	DR97_4112	DR97_3889	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	thiE- thiamine-phosphate pyrophosphorylase	0.658
purL	thiL	DR97_4112	DR97_3816	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family	0.430
ribD	guaA	DR97_3811	DR97_4101	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.692

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