STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
GTP 3’,8-cyclase; Catalyzes the cyclization of GTP to (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate; Belongs to the radical SAM superfamily. MoaA family (329 aa)
Predicted Functional Partners:
Cyclic pyranopterin monophosphate synthase; Catalyzes the conversion of (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family (160 aa)
Molybdopterin molybdenumtransferase; Molyb_syn- molybdenum cofactor synthesis domain protein (405 aa)
Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin (179 aa)
Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin (185 aa)
folE- GTP cyclohydrolase I (186 aa)
folE- GTP cyclohydrolase I (181 aa)
annotation not available (150 aa)
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family (365 aa)
GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5’-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family (205 aa)
GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate (298 aa)