dnaX protein (Pseudomonas aeruginosa) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Score

dnaX

DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity (695 aa)

Predicted Functional Partners:

dnaN

0.999

holA

0.999

dnaE_2

0.997

holB

0.996

dnaQ

0.975

holC

0.971

polA

0.962

ndk

0.933

nrdD

0.908

dcd

0.903

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dcd	dnaE_2	DR97_4441	DR97_4299	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	Polc- DNA polymerase III, alpha subunit	0.900
dcd	dnaN	DR97_4441	DR97_2951	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...]	0.915
dcd	dnaQ	DR97_4441	DR97_63	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3’-5’ exonuclease	0.900
dcd	dnaX	DR97_4441	DR97_404	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity	0.903
dcd	holA	DR97_4441	DR97_3876	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	holA- DNA polymerase III, delta subunit	0.905
dcd	holB	DR97_4441	DR97_4978	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	holB- DNA polymerase III, delta’ subunit	0.914
dcd	holC	DR97_4441	DR97_4034	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	annotation not available	0.914
dcd	ndk	DR97_4441	DR97_4062	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	0.933
dcd	nrdD	DR97_4441	DR97_5925	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	nrdD- anaerobic ribonucleoside-triphosphate reductase	0.915
dcd	polA	DR97_4441	DR97_2871	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity	0.943
dnaE_2	dcd	DR97_4299	DR97_4441	Polc- DNA polymerase III, alpha subunit	dCTP_deam- deoxycytidine triphosphate deaminase; Belongs to the dCTP deaminase family	0.900
dnaE_2	dnaN	DR97_4299	DR97_2951	Polc- DNA polymerase III, alpha subunit	Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...]	0.997
dnaE_2	dnaQ	DR97_4299	DR97_63	Polc- DNA polymerase III, alpha subunit	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3’-5’ exonuclease	0.997
dnaE_2	dnaX	DR97_4299	DR97_404	Polc- DNA polymerase III, alpha subunit	DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity	0.997
dnaE_2	holA	DR97_4299	DR97_3876	Polc- DNA polymerase III, alpha subunit	holA- DNA polymerase III, delta subunit	0.952
dnaE_2	holB	DR97_4299	DR97_4978	Polc- DNA polymerase III, alpha subunit	holB- DNA polymerase III, delta’ subunit	0.945
dnaE_2	holC	DR97_4299	DR97_4034	Polc- DNA polymerase III, alpha subunit	annotation not available	0.921
dnaE_2	ndk	DR97_4299	DR97_4062	Polc- DNA polymerase III, alpha subunit	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	0.909
dnaE_2	nrdD	DR97_4299	DR97_5925	Polc- DNA polymerase III, alpha subunit	nrdD- anaerobic ribonucleoside-triphosphate reductase	0.909
dnaE_2	polA	DR97_4299	DR97_2871	Polc- DNA polymerase III, alpha subunit	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity	0.990

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