purL protein (Pseudomonas aeruginosa) - STRING interaction network

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purL

Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1298 aa)

Predicted Functional Partners:

purF

0.999

purM

0.999

purH

0.999

purD

0.999

purN

0.999

purC

0.999

purK

0.994

purT

0.991

guaA

0.988

PA2396

0.987

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PA2396	guaA	DR97_6036	DR97_4101	annotation not available	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.709
PA2396	purC	DR97_6036	DR97_934	annotation not available	purC- phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family	0.878
PA2396	purD	DR97_6036	DR97_2206	annotation not available	purD- phosphoribosylamine--glycine ligase; Belongs to the GARS family	0.875
PA2396	purF	DR97_6036	DR97_4825	annotation not available	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family	0.901
PA2396	purH	DR97_6036	DR97_2205	annotation not available	Bifunctional purine biosynthesis protein PurH; purH- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	0.888
PA2396	purK	DR97_6036	DR97_2802	annotation not available	N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	0.540
PA2396	purL	DR97_6036	DR97_4112	annotation not available	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	0.987
PA2396	purM	DR97_6036	DR97_993	annotation not available	annotation not available	0.887
guaA	PA2396	DR97_4101	DR97_6036	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	annotation not available	0.709
guaA	purC	DR97_4101	DR97_934	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	purC- phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family	0.963
guaA	purD	DR97_4101	DR97_2206	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	purD- phosphoribosylamine--glycine ligase; Belongs to the GARS family	0.983
guaA	purF	DR97_4101	DR97_4825	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family	0.961
guaA	purH	DR97_4101	DR97_2205	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Bifunctional purine biosynthesis protein PurH; purH- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	0.975
guaA	purK	DR97_4101	DR97_2802	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	0.850
guaA	purL	DR97_4101	DR97_4112	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	0.988
guaA	purM	DR97_4101	DR97_993	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	annotation not available	0.931
guaA	purN	DR97_4101	DR97_994	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	purN- phosphoribosylglycinamide formyltransferase	0.800
guaA	purT	DR97_4101	DR97_4125	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Formate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family	0.639
purC	PA2396	DR97_934	DR97_6036	purC- phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family	annotation not available	0.878
purC	guaA	DR97_934	DR97_4101	purC- phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.963

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