Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aprA | cbpD | DR97_688 | DR97_1092 | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | Chitin binding domain protein; Binds chitin but does not hydrolyze it, has no detectable protease or staphylolytic activity | 0.683 |
| aprA | lasA | DR97_688 | DR97_4 | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | Lasa protease precursor; Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly- Gly-|-X substrates where X is Ala or Gly . Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases . Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in [...] | 0.865 |
| aprA | lasB | DR97_688 | DR97_4154 | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | Pseudolysin; Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase . Autocatalyses processing of its pro-peptide Processes the pro-peptide of pro-chitin-binding protein (cbpD) . Involved in the pathogenesis of P.aeruginosa infections | 0.904 |
| aprA | lasI | DR97_688 | DR97_591 | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | Acyl homoserine lactone synthase; Required for the synthesis of PAI consisting of 3-oxo-N- (tetrahydro-2-oxo-3-furanyl)-dodecanamide also known as N-(3- oxododecanoyl)homoserine lactone, an autoinducer molecule which binds to LasR and thus acts in elastase biosynthesis regulation | 0.860 |
| aprA | lasR | DR97_688 | DR97_592 | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | Luxr family transcriptional regulator, quorum-sensing system regulator lasr; Transcriptional activator of elastase structural gene (LasB). Binds to the PAI autoinducer | 0.848 |
| aprA | lecA | DR97_688 | DR97_5600 | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | Pa-i galactophilic lectin; D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl- beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity | 0.674 |
| aprA | plcH | DR97_688 | DR97_1100 | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | Phospholipase c, phosphocholine-specific; Hydrolyzes sphingomyelin in addition to phosphatidylcholine | 0.849 |
| aprA | plcN | DR97_688 | DR97_4608 | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | Phospholipase c, phosphocholine-specific; Hydrolyzes phosphatidylserine as well as phosphatidylcholine | 0.848 |
| aprA | rhlI | DR97_688 | DR97_4445 | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | Autoinducer synthetase family protein; Required for the synthesis of BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone) autoinducer molecules which bind to RhlR and thus acts in elastase biosynthesis regulation | 0.713 |
| cbpD | aprA | DR97_1092 | DR97_688 | Chitin binding domain protein; Binds chitin but does not hydrolyze it, has no detectable protease or staphylolytic activity | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | 0.683 |
| cbpD | lasA | DR97_1092 | DR97_4 | Chitin binding domain protein; Binds chitin but does not hydrolyze it, has no detectable protease or staphylolytic activity | Lasa protease precursor; Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly- Gly-|-X substrates where X is Ala or Gly . Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases . Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in [...] | 0.685 |
| cbpD | lasB | DR97_1092 | DR97_4154 | Chitin binding domain protein; Binds chitin but does not hydrolyze it, has no detectable protease or staphylolytic activity | Pseudolysin; Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase . Autocatalyses processing of its pro-peptide Processes the pro-peptide of pro-chitin-binding protein (cbpD) . Involved in the pathogenesis of P.aeruginosa infections | 0.924 |
| cbpD | plcH | DR97_1092 | DR97_1100 | Chitin binding domain protein; Binds chitin but does not hydrolyze it, has no detectable protease or staphylolytic activity | Phospholipase c, phosphocholine-specific; Hydrolyzes sphingomyelin in addition to phosphatidylcholine | 0.406 |
| lasA | aprA | DR97_4 | DR97_688 | Lasa protease precursor; Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly- Gly-|-X substrates where X is Ala or Gly . Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases . Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in [...] | Alkaline metalloproteinase precursor; Belongs to the peptidase M10B family | 0.865 |
| lasA | cbpD | DR97_4 | DR97_1092 | Lasa protease precursor; Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly- Gly-|-X substrates where X is Ala or Gly . Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases . Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in [...] | Chitin binding domain protein; Binds chitin but does not hydrolyze it, has no detectable protease or staphylolytic activity | 0.685 |
| lasA | lasB | DR97_4 | DR97_4154 | Lasa protease precursor; Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly- Gly-|-X substrates where X is Ala or Gly . Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases . Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in [...] | Pseudolysin; Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase . Autocatalyses processing of its pro-peptide Processes the pro-peptide of pro-chitin-binding protein (cbpD) . Involved in the pathogenesis of P.aeruginosa infections | 0.937 |
| lasA | lasI | DR97_4 | DR97_591 | Lasa protease precursor; Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly- Gly-|-X substrates where X is Ala or Gly . Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases . Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in [...] | Acyl homoserine lactone synthase; Required for the synthesis of PAI consisting of 3-oxo-N- (tetrahydro-2-oxo-3-furanyl)-dodecanamide also known as N-(3- oxododecanoyl)homoserine lactone, an autoinducer molecule which binds to LasR and thus acts in elastase biosynthesis regulation | 0.863 |
| lasA | lasR | DR97_4 | DR97_592 | Lasa protease precursor; Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly- Gly-|-X substrates where X is Ala or Gly . Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases . Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in [...] | Luxr family transcriptional regulator, quorum-sensing system regulator lasr; Transcriptional activator of elastase structural gene (LasB). Binds to the PAI autoinducer | 0.855 |
| lasA | lecA | DR97_4 | DR97_5600 | Lasa protease precursor; Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly- Gly-|-X substrates where X is Ala or Gly . Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases . Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in [...] | Pa-i galactophilic lectin; D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl- beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity | 0.844 |
| lasA | plcN | DR97_4 | DR97_4608 | Lasa protease precursor; Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly- Gly-|-X substrates where X is Ala or Gly . Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases . Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in [...] | Phospholipase c, phosphocholine-specific; Hydrolyzes phosphatidylserine as well as phosphatidylcholine | 0.487 |
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