STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mmsRTranscriptional regulator; Regulatory protein for the mmsAB operon. Activates the transcription of the mmsAB genes (307 aa)    
Predicted Functional Partners:
cdhR
Helix-turn-helix domain protein; Induces the transcription of the PA5384-PA5388 operon in response to carnitine. This operon is involved in the degradation of L- carnitine, and allows P.aeruginosa to grow on L-carnitine as the sole source of carbon and nitrogen
 
 
 0.908
YeaM
annotation not available
  
 
 0.887
xylS
annotation not available
 
 
 
 0.885
mmsA
Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family
     
 0.870
mmsB
HIBADH: 3-hydroxyisobutyrate dehydrogenase; Belongs to the 3-hydroxyisobutyrate dehydrogenase family
  
  
 0.860
DR97_3269
annotation not available
 
 
 
 0.810
DR97_1237
Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase; MMSDH: methylmalonate-semialdehyde dehydrogenase
     
 0.709
bauC
Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase; Involved in the degradation of beta-alanine
     
 0.705
DR97_1241
Putative 3-hydroxyisobutyrate dehydrogenase; NAD-dependent L-serine dehydrogenase that catalyzes the oxidation of L-serine and methyl-L-serine and is possibly involved in serine catabolism. Has low activity toward beta-hydroxyisobutyrate
  
  
 0.698
pchR
Arac family transcriptional regulator, transcriptional activator of the genes for pyochelin and ferripyochelin receptors; Positive activator of the genes for pyochelin and ferripyochelin receptors
 
 
 
 0.691
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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