pfkB protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

pfkB

pfkB- 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family (314 aa)

Predicted Functional Partners:

fruA

0.999

fruI

0.999

fbp

0.988

fba

0.975

nagF

0.911

fruR

0.877

pgi

0.865

ppsA

0.827

tpiA

0.817

nagE

0.806

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
fba	fbp	DR97_3524	DR97_2464	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	annotation not available	0.988
fba	fruA	DR97_3524	DR97_4382	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	FRU- PTS system, Fru family, IIB component domain protein	0.982
fba	fruI	DR97_3524	DR97_4380	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	Phosphotransferase system transporter enzyme I, FruI; PTS_I_fam- phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family	0.974
fba	nagE	DR97_3524	DR97_4115	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	PTS-II-BC-nag- PTS system, N-acetylglucosamine-specific IIBC component	0.666
fba	nagF	DR97_3524	DR97_4116	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	PTS_I_fam- phosphoenolpyruvate-protein phosphotransferase	0.781
fba	pfkB	DR97_3524	DR97_4381	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	pfkB- 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family	0.975
fba	pgi	DR97_3524	DR97_2075	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	annotation not available	0.990
fba	ppsA	DR97_3524	DR97_116	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family	0.816
fba	tpiA	DR97_3524	DR97_2092	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family	0.997
fbp	fba	DR97_2464	DR97_3524	annotation not available	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	0.988
fbp	fruI	DR97_2464	DR97_4380	annotation not available	Phosphotransferase system transporter enzyme I, FruI; PTS_I_fam- phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family	0.612
fbp	fruR	DR97_2464	DR97_4379	annotation not available	annotation not available	0.615
fbp	nagF	DR97_2464	DR97_4116	annotation not available	PTS_I_fam- phosphoenolpyruvate-protein phosphotransferase	0.496
fbp	pfkB	DR97_2464	DR97_4381	annotation not available	pfkB- 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family	0.988
fbp	pgi	DR97_2464	DR97_2075	annotation not available	annotation not available	0.972
fbp	ppsA	DR97_2464	DR97_116	annotation not available	Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family	0.791
fbp	tpiA	DR97_2464	DR97_2092	annotation not available	Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family	0.840
fruA	fba	DR97_4382	DR97_3524	FRU- PTS system, Fru family, IIB component domain protein	fruBisAldo_II_B- fructose-bisphosphate aldolase, class II, Calvin cycle subtype	0.982
fruA	fruI	DR97_4382	DR97_4380	FRU- PTS system, Fru family, IIB component domain protein	Phosphotransferase system transporter enzyme I, FruI; PTS_I_fam- phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family	0.999
fruA	fruR	DR97_4382	DR97_4379	FRU- PTS system, Fru family, IIB component domain protein	annotation not available	0.886

page 1 of 6

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2020

Credits

Access

Info

About