STRINGSTRING
nth protein (Pseudomonas aeruginosa) - STRING interaction network
"nth" - Endonuclease III in Pseudomonas aeruginosa
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (212 aa)    
Predicted Functional Partners:
rnfE
Electron transport complex subunit E; Part of a membrane complex involved in electron transport (238 aa)
 
   
  0.974
rnfB
rnfB- electron transport complex, RnfABCDGE type, B subunit (188 aa)
   
   
  0.970
rnfG
Electron transport complex subunit G; Part of a membrane complex involved in electron transport (214 aa)
   
   
  0.929
rnfD
Electron transport complex subunit D; Part of a membrane complex involved in electron transport (344 aa)
   
   
  0.925
rnfA
Electron transport complex subunit A; Part of a membrane complex involved in electron transport (194 aa)
       
  0.922
rnfC
Electron transport complex subunit C; Part of a membrane complex involved in electron transport; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily (774 aa)
   
   
  0.918
xth
exoDNase_III- exodeoxyribonuclease III (270 aa)
 
 
  0.915
mutM
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3’- and 5’-phosphates (270 aa)
   
   
  0.879
DR97_5076
annotation not available (476 aa)
           
  0.854
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (913 aa)
   
 
  0.828
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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