mdtN_3 protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

mdtN_3

Multidrug resistance protein MdtN; RND_mfp- efflux transporter, RND family, MFP subunit (323 aa)

Predicted Functional Partners:

DR97_4522

0.987

yhhJ_2

0.985

DR97_4523

0.668

psiE

0.608

macB

0.576

DR97_1552

0.486

DR97_5466

0.470

acrB

0.458

acrD

0.452

bepE1

0.452

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_1552	acrD	DR97_1552	DR97_5829	annotation not available	2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein	0.829
DR97_1552	mdtN_3	DR97_1552	DR97_4520	annotation not available	Multidrug resistance protein MdtN; RND_mfp- efflux transporter, RND family, MFP subunit	0.486
DR97_4522	DR97_4523	DR97_4522	DR97_4523	annotation not available	Putative periplasmic lipoprotein	0.668
DR97_4522	macB	DR97_4522	DR97_6042	annotation not available	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	0.624
DR97_4522	mdtN_3	DR97_4522	DR97_4520	annotation not available	Multidrug resistance protein MdtN; RND_mfp- efflux transporter, RND family, MFP subunit	0.987
DR97_4522	psiE	DR97_4522	DR97_4519	annotation not available	annotation not available	0.582
DR97_4522	yhhJ_2	DR97_4522	DR97_4521	annotation not available	annotation not available	0.961
DR97_4523	DR97_4522	DR97_4523	DR97_4522	Putative periplasmic lipoprotein	annotation not available	0.668
DR97_4523	mdtN_3	DR97_4523	DR97_4520	Putative periplasmic lipoprotein	Multidrug resistance protein MdtN; RND_mfp- efflux transporter, RND family, MFP subunit	0.668
DR97_4523	psiE	DR97_4523	DR97_4519	Putative periplasmic lipoprotein	annotation not available	0.449
DR97_4523	yhhJ_2	DR97_4523	DR97_4521	Putative periplasmic lipoprotein	annotation not available	0.668
DR97_5466	macB	DR97_5466	DR97_6042	RND_mfp- efflux transporter, RND family, MFP subunit	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	0.600
DR97_5466	mdtN_3	DR97_5466	DR97_4520	RND_mfp- efflux transporter, RND family, MFP subunit	Multidrug resistance protein MdtN; RND_mfp- efflux transporter, RND family, MFP subunit	0.470
acrB	macB	DR97_1904	DR97_6042	2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	0.894
acrB	mdtN_3	DR97_1904	DR97_4520	2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein	Multidrug resistance protein MdtN; RND_mfp- efflux transporter, RND family, MFP subunit	0.458
acrD	DR97_1552	DR97_5829	DR97_1552	2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein	annotation not available	0.829
acrD	macB	DR97_5829	DR97_6042	2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	0.894
acrD	mdtN_3	DR97_5829	DR97_4520	2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein	Multidrug resistance protein MdtN; RND_mfp- efflux transporter, RND family, MFP subunit	0.452
bepE1	macB	DR97_4420	DR97_6042	2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	0.481
bepE1	mdtN_3	DR97_4420	DR97_4520	2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein	Multidrug resistance protein MdtN; RND_mfp- efflux transporter, RND family, MFP subunit	0.452

page 1 of 3

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2019

Credits

Access

Info

About