node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_1225 | ubiG | DR97_1225 | DR97_4765 | annotation not available | 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway | 0.772 |
DR97_1225 | ubiH | DR97_1225 | DR97_2592 | annotation not available | ubiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase | 0.852 |
DR97_2590 | DR97_5238 | DR97_2590 | DR97_5238 | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | annotation not available | 0.900 |
DR97_2590 | ubiA | DR97_2590 | DR97_2729 | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate | 0.805 |
DR97_2590 | ubiE | DR97_2590 | DR97_2418 | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | Demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2) | 0.708 |
DR97_2590 | ubiG | DR97_2590 | DR97_4765 | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway | 0.990 |
DR97_2590 | ubiH | DR97_2590 | DR97_2592 | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | ubiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase | 0.902 |
DR97_4766 | YciK | DR97_4766 | DR97_4763 | 5-methylthioadenosine/S-adenosylhomocysteinedeaminase; 465; amidohydrolase family Protein OLEI01672_1_465 | annotation not available | 0.489 |
DR97_4766 | mupP | DR97_4766 | DR97_4764 | 5-methylthioadenosine/S-adenosylhomocysteinedeaminase; 465; amidohydrolase family Protein OLEI01672_1_465 | N-acetyl-d-muramate 6-phosphate phosphatase; Specifically catalyzes the dephosphorylation of N- acetylmuramate 6-phosphate (MurNAc-6P) to MurNac (By similarity). Is involved in peptidoglycan recycling as part of a cell wall recycling pathway that bypasses de novo biosynthesis of the peptidoglycan precursor UDP-MurNAc . Plays a role in intrinsic resistance to fosfomycin, which targets the de novo synthesis of UDP- MurNAc | 0.780 |
DR97_4766 | ubiG | DR97_4766 | DR97_4765 | 5-methylthioadenosine/S-adenosylhomocysteinedeaminase; 465; amidohydrolase family Protein OLEI01672_1_465 | 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway | 0.759 |
DR97_5238 | DR97_2590 | DR97_5238 | DR97_2590 | annotation not available | 2-octaprenyl-3-methyl-6-methoxy-1, 4-benzoquinolhydroxylase; ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein | 0.900 |
DR97_5238 | coq7 | DR97_5238 | DR97_3608 | annotation not available | 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis | 0.900 |
DR97_5238 | ubiG | DR97_5238 | DR97_4765 | annotation not available | 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway | 0.800 |
DR97_5238 | ubiH | DR97_5238 | DR97_2592 | annotation not available | ubiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase | 0.900 |
YciK | DR97_4766 | DR97_4763 | DR97_4766 | annotation not available | 5-methylthioadenosine/S-adenosylhomocysteinedeaminase; 465; amidohydrolase family Protein OLEI01672_1_465 | 0.489 |
YciK | mupP | DR97_4763 | DR97_4764 | annotation not available | N-acetyl-d-muramate 6-phosphate phosphatase; Specifically catalyzes the dephosphorylation of N- acetylmuramate 6-phosphate (MurNAc-6P) to MurNac (By similarity). Is involved in peptidoglycan recycling as part of a cell wall recycling pathway that bypasses de novo biosynthesis of the peptidoglycan precursor UDP-MurNAc . Plays a role in intrinsic resistance to fosfomycin, which targets the de novo synthesis of UDP- MurNAc | 0.874 |
YciK | ubiG | DR97_4763 | DR97_4765 | annotation not available | 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway | 0.821 |
coq7 | DR97_5238 | DR97_3608 | DR97_5238 | 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis | annotation not available | 0.900 |
coq7 | ubiA | DR97_3608 | DR97_2729 | 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate | 0.496 |
coq7 | ubiE | DR97_3608 | DR97_2418 | 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis | Demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2) | 0.921 |