| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DR97_4950 | DR97_4951 | DR97_4950 | DR97_4951 | annotation not available | Hypothetical protein; lolCE- liporeleasing system, transmembrane , LolC/E family protein | 0.640 |
| DR97_4950 | lolC | DR97_4950 | DR97_4953 | annotation not available | lolCE- liporeleasing system, transmembrane , LolC/E family protein | 0.515 |
| DR97_4950 | lolD | DR97_4950 | DR97_4952 | annotation not available | Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner | 0.713 |
| DR97_4951 | DR97_4950 | DR97_4951 | DR97_4950 | Hypothetical protein; lolCE- liporeleasing system, transmembrane , LolC/E family protein | annotation not available | 0.640 |
| DR97_4951 | PA2389 | DR97_4951 | DR97_6043 | Hypothetical protein; lolCE- liporeleasing system, transmembrane , LolC/E family protein | RND_mfp- efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 0.579 |
| DR97_4951 | lolB | DR97_4951 | DR97_1977 | Hypothetical protein; lolCE- liporeleasing system, transmembrane , LolC/E family protein | Outer-membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein | 0.951 |
| DR97_4951 | lolC | DR97_4951 | DR97_4953 | Hypothetical protein; lolCE- liporeleasing system, transmembrane , LolC/E family protein | lolCE- liporeleasing system, transmembrane , LolC/E family protein | 0.946 |
| DR97_4951 | lolD | DR97_4951 | DR97_4952 | Hypothetical protein; lolCE- liporeleasing system, transmembrane , LolC/E family protein | Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner | 0.993 |
| DR97_4951 | macB | DR97_4951 | DR97_6042 | Hypothetical protein; lolCE- liporeleasing system, transmembrane , LolC/E family protein | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides | 0.777 |
| PA2389 | DR97_4951 | DR97_6043 | DR97_4951 | RND_mfp- efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Hypothetical protein; lolCE- liporeleasing system, transmembrane , LolC/E family protein | 0.579 |
| PA2389 | lolB | DR97_6043 | DR97_1977 | RND_mfp- efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Outer-membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein | 0.627 |
| PA2389 | lolC | DR97_6043 | DR97_4953 | RND_mfp- efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | lolCE- liporeleasing system, transmembrane , LolC/E family protein | 0.579 |
| PA2389 | lolD | DR97_6043 | DR97_4952 | RND_mfp- efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner | 0.715 |
| PA2389 | macB | DR97_6043 | DR97_6042 | RND_mfp- efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides | 0.999 |
| ffh | ftsY | DR97_4130 | DR97_3340 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components | 0.996 |
| ffh | ksgA | DR97_4130 | DR97_3561 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | 0.856 |
| ffh | lolD | DR97_4130 | DR97_4952 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner | 0.769 |
| ffh | serS | DR97_4130 | DR97_5350 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) | 0.767 |
| ftsY | ffh | DR97_3340 | DR97_4130 | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.996 |
| ftsY | ksgA | DR97_3340 | DR97_3561 | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | 0.878 |
