node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddl | murA | DR97_1588 | DR97_1628 | D-alanine-d-alanine ligase; Cell wall formation | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | 0.950 |
ddl | murB | DR97_1588 | DR97_4962 | D-alanine-d-alanine ligase; Cell wall formation | Udp-n-acetylenolpyruvoylglucosamine reductase; Cell wall formation | 0.964 |
ddl | murC | DR97_1588 | DR97_1589 | D-alanine-d-alanine ligase; Cell wall formation | Udp-n-acetylmuramate--alanine ligase; Cell wall formation | 0.999 |
ddl | murD | DR97_1588 | DR97_1592 | D-alanine-d-alanine ligase; Cell wall formation | Udp-n-acetylmuramoyl-l-alanyl-d-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) | 0.993 |
ddl | murE | DR97_1588 | DR97_1595 | D-alanine-d-alanine ligase; Cell wall formation | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan | 0.994 |
ddl | murF | DR97_1588 | DR97_1594 | D-alanine-d-alanine ligase; Cell wall formation | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein | 0.999 |
ddl | murG | DR97_1588 | DR97_1590 | D-alanine-d-alanine ligase; Cell wall formation | Udp-n-acetylglucosamine--n-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol n-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) | 0.989 |
kdsB | murA | DR97_4960 | DR97_1628 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | 0.639 |
kdsB | murB | DR97_4960 | DR97_4962 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | Udp-n-acetylenolpyruvoylglucosamine reductase; Cell wall formation | 0.968 |
kdsB | murD | DR97_4960 | DR97_1592 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | Udp-n-acetylmuramoyl-l-alanyl-d-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) | 0.401 |
kdsB | murF | DR97_4960 | DR97_1594 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein | 0.410 |
kdsB | murG | DR97_4960 | DR97_1590 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | Udp-n-acetylglucosamine--n-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol n-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) | 0.455 |
kdsB | ptpA | DR97_4960 | DR97_4961 | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | Belongs to the low molecular weight phosphotyrosine protein phosphatase family | 0.933 |
murA | ddl | DR97_1628 | DR97_1588 | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | D-alanine-d-alanine ligase; Cell wall formation | 0.950 |
murA | kdsB | DR97_1628 | DR97_4960 | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | 0.639 |
murA | murB | DR97_1628 | DR97_4962 | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | Udp-n-acetylenolpyruvoylglucosamine reductase; Cell wall formation | 0.996 |
murA | murC | DR97_1628 | DR97_1589 | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | Udp-n-acetylmuramate--alanine ligase; Cell wall formation | 0.980 |
murA | murD | DR97_1628 | DR97_1592 | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | Udp-n-acetylmuramoyl-l-alanyl-d-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) | 0.977 |
murA | murE | DR97_1628 | DR97_1595 | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan | 0.972 |
murA | murF | DR97_1628 | DR97_1594 | Udp-n-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein | 0.966 |