The upcoming version of STRING is available for preview: it includes new data, new enrichment categories (e.g. diseases and tissues) and covers 14000 fully sequenced genomes.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilZ
annotation not available (118 aa)
Predicted Functional Partners:
fimX
GGDEF: diguanylate cyclase domain protein
0.978
lapD
annotation not available
0.953
rocR
annotation not available
0.916
pleD_6
Response regulator PleD; GGDEF: diguanylate cyclase domain protein
0.906
wspR
Two-component response regulator; GGDEF: diguanylate cyclase domain protein
STRING Data Update
