ycfH protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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Predicted Interactions

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Score

ycfH

annotation not available (258 aa)

Predicted Functional Partners:

holB

0.931

pilZ

0.867

tmk

0.856

pabC

0.795

mltG

0.765

fabF1

0.668

acpP_1

0.603

polA

0.598

plsX

0.547

ftsY

0.538

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acpP_1	fabF1	DR97_4973	DR97_4974	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	0.992
acpP_1	holB	DR97_4973	DR97_4978	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	holB- DNA polymerase III, delta’ subunit	0.723
acpP_1	mltG	DR97_4973	DR97_4976	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	Endolytic murein transglycosylase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	0.688
acpP_1	pabC	DR97_4973	DR97_4975	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	pabC_Proteo- aminodeoxychorismate lyase	0.717
acpP_1	pilZ	DR97_4973	DR97_4979	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	annotation not available	0.615
acpP_1	plsX	DR97_4973	DR97_4970	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	0.887
acpP_1	polA	DR97_4973	DR97_2871	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity	0.506
acpP_1	tmk	DR97_4973	DR97_4977	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	0.801
acpP_1	ycfH	DR97_4973	DR97_4980	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	annotation not available	0.603
fabF1	acpP_1	DR97_4974	DR97_4973	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	0.992
fabF1	holB	DR97_4974	DR97_4978	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	holB- DNA polymerase III, delta’ subunit	0.833
fabF1	mltG	DR97_4974	DR97_4976	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	Endolytic murein transglycosylase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	0.866
fabF1	pabC	DR97_4974	DR97_4975	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	pabC_Proteo- aminodeoxychorismate lyase	0.900
fabF1	pilZ	DR97_4974	DR97_4979	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	annotation not available	0.691
fabF1	plsX	DR97_4974	DR97_4970	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	0.879
fabF1	tmk	DR97_4974	DR97_4977	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	0.812
fabF1	ycfH	DR97_4974	DR97_4980	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	annotation not available	0.668
ftsY	holB	DR97_3340	DR97_4978	Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	holB- DNA polymerase III, delta’ subunit	0.464
ftsY	polA	DR97_3340	DR97_2871	Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity	0.854
ftsY	tmk	DR97_3340	DR97_4977	Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	0.420

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