STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR97_4982annotation not available (212 aa)    
Predicted Functional Partners:
DR97_4489
annotation not available
      
 0.854
DR97_4981
annotation not available
 
     0.766
DR97_4984
DUF4823 domain-containing protein
 
     0.742
amrZ
Functions as both a transcriptional activator and repressor of multiple genes encoding virulence factors as well as genes involved in environmental adaptation (PubMed:16352829, PubMed:26549743, PubMed:22511872). Plays a role in alginate production via the activation of AlgD which is the first gene in the alginate biosynthetic operon . Regulates also the transcription of genes responsible for type IV pili localization and twitching motility . Mediates transition of P.aeruginosa biofilm infections from colonizing to chronic biofilms through repression of the psl operon . Represses also i [...]
  
   
 0.712
DR97_2718
Uncharacterized protein
  
     0.678
DR97_2345
Probably functions as a FAD-dependent oxidoreductase, whose physiological substrate is unknown. Does not display amino-acid oxidase or glycerol-3-phosphate dehydrogenase activities . Is essential for growth of P.aeruginosa in the sputum of cystic fibrosis patients
  
     0.666
DR97_4985
Proteophosphoglycan
 
    0.641
DR97_489
MFS transporter
  
     0.591
YpuG
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
   
  
 0.579
murG
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
      
 0.574
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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