STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR97_5095Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family (284 aa)    
Predicted Functional Partners:
DR97_5096
Hypothetical protein; DUF1127 domain-containing protein
 
     0.715
DR97_5011
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
  
    0.678
DR97_4092
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
  
     0.662
DR97_3190
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
  
     0.609
DR97_2815
Lysr family transcriptional regulator, putative pyruvate carboxylase regulator; Belongs to the LysR transcriptional regulatory family
  
     0.578
DR97_5771
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
  
     0.553
YeiE
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
  
    0.549
DR97_1166
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
  
     0.528
DR97_5097
annotation not available
  
    0.528
trpI
Bacterial regulatory helix-turn-helix , lysr family protein; Activates the expression of the trpBA genes, which encode the two tryptophan synthase subunits, and represses initiation at its own promoter. Acts by binding to two adjacent sites in the intergenic region. In the absence of the inducer indoleglycerol phosphate (InGP), TrpI binds to site I. In the presence of InGP, TrpI binds to site I and site II. Binding to site II is site I dependent. InGP strongly stimulates binding to site II and is required for maximal activation of trpBA
  
    0.527
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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