STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR97_514annotation not available (86 aa)    
Predicted Functional Partners:
vgrG2a
Part of the H2 type VI secretion system (H2-T6SS) specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection . May form the spike at the tip of the elongating tube formed by haemolysin co-regulated protein 2a/Hcp2a. In turn, may allow the delivery of the Tle4 antibacterial toxin to target cells where it exerts its toxicity (Probable). Promotes also the release of VgrG2b toxin to the host cell
 
  
 0.935
DR97_512
annotation not available
 
     0.921
DR97_513
Conserved hypothetical protein
 
     0.895
DR97_3223
annotation not available
 
     0.662
vgrG2b
Part of the H2 type VI secretion system (H2-T6SS) specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection (PubMed:26037124, PubMed:31577948, PubMed:31231326). Forms the spike at the tip of the elongating tube probably formed by haemolysin co-regulated protein 2b/Hcp2b (Probable). Allows the delivery of the Tle3 antibacterial toxin to target cells where it exerts its toxicity . Additionally, acts directly as an effector and promotes internalization by interacting with the host gamma-tubulin ring complex . Elicits t [...]
 
  
 0.655
DR97_3219
Conserved hypothetical protein
 
     0.647
DR97_510
annotation not available
 
   
 0.635
DR97_3218
Uncharacterized protein
  
     0.552
DR97_3962
annotation not available
  
     0.477
DR97_228
Uncharacterized protein
 
     0.424
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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