STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyiPutative hydroxypyruvate isomerase; Belongs to the hyi family (260 aa)    
Predicted Functional Partners:
gcl
Tartronate-semialdehyde synthase; Belongs to the TPP enzyme family
 
 
 0.991
GlxR
Tartro_sem_red: 2-hydroxy-3-oxopropionate reductase
 
 
 0.987
hprA
D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
  
 
 0.916
DR97_3970
D-isomer specific 2-hydroxyacid dehydrogenase, nad binding domain protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
  
 
 0.908
TtuD
Hypothetical protein; Putative hydroxypyruvate reductase
 
  
 0.643
DR97_519
Hypothetical protein; Heme-degrading domain-containing protein
 
    0.533
eta
Exotoxin a precursor; An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38
      
 0.487
DR97_4615
annotation not available
 
  
 0.457
DR97_359
annotation not available
 
  
 0.425
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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