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tpx protein (Pseudomonas aeruginosa) - STRING interaction network
"tpx" - Thiol peroxidase in Pseudomonas aeruginosa
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily (165 aa)    
Predicted Functional Partners:
katE
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide (709 aa)
   
 
  0.843
bcp
annotation not available (157 aa)
   
   
  0.842
tsaA
Alkyl hydroperoxide reductase; C-terminal domain of 1-Cys peroxiredoxin family protein (200 aa)
   
   
  0.841
ahpC
Alkyl hydroperoxide reductase subunit C; ahpC- peroxiredoxin (187 aa)
   
   
  0.840
katB
annotation not available (513 aa)
     
   
  0.790
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (913 aa)
         
  0.765
katA
annotation not available (482 aa)
     
   
  0.763
bsaA
annotation not available (161 aa)
         
  0.750
DR97_1543
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (193 aa)
   
   
  0.721
cinC
annotation not available (150 aa)
     
   
  0.709
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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