STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mexTannotation not available (304 aa)    
Predicted Functional Partners:
mexE
Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
  
  
 0.935
oprN
outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein
     
 0.915
mexF
2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein
     
 0.909
mexR
Marr family transcriptional regulator, repressor of the mexab-oprm multidrug resistance operon; Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon
      
 0.863
nalD
annotation not available
    
 
 0.858
NfxB
annotation not available
    
 
 0.857
nfxB
Tetr/acrr family transcriptional regulator, mexcd-oprj operon repressor; Confers resistance to guinolones. May negatively regulate the expression of genes that are associated with cell permeability to drugs
    
 
 0.857
oprJ
Outer membrane protein, multidrug efflux system; Channel-forming component of a multidrug resistance efflux pump
      
 0.854
MexE
Membrane fusion protein, gold/copper resistance efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
     
 0.854
opdC
annotation not available
      
 0.851
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.