node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pyc | birA | DR97_623 | DR97_3627 | Putative pyruvate carboxylase; Carbamoyl-phosphate synthase L chain, N-terminal domain protein | Bira family transcriptional regulator, biotin operon repressor / biotin---[acetyl-coa-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon | 0.998 |
Pyc | liuD | DR97_623 | DR97_5836 | Putative pyruvate carboxylase; Carbamoyl-phosphate synthase L chain, N-terminal domain protein | annotation not available | 0.869 |
atuC | birA | DR97_5053 | DR97_3627 | annotation not available | Bira family transcriptional regulator, biotin operon repressor / biotin---[acetyl-coa-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon | 0.520 |
atuC | liuA | DR97_5053 | DR97_5833 | annotation not available | Citronelloyl-coa dehydrogenase; Isovaleryl-CoA dehydrogenase 1, mitochondrial; acyl-CoA dehydrogenase, N-terminal domain protein | 0.642 |
atuC | liuD | DR97_5053 | DR97_5836 | annotation not available | annotation not available | 0.867 |
atuC | liuE | DR97_5053 | DR97_5837 | annotation not available | Hydroxymethylglutaryl-coa lyase; Involved in the L-leucine, isovalerate and acyclic monoterpene catabolism. Catalyzes the cleavage of 3-hydroxy-3- methylglutaryl-CoA (HMG-CoA) to yield acetyl-CoA and acetoacetate. It can also catalyze the cleavage of 3-hydroxy-3-isohexenylglutaryl-CoA (HIHG_CoA) to yield 7-methyl-3-oxooct-6-enoyl-CoA and acetate | 0.733 |
birA | Pyc | DR97_3627 | DR97_623 | Bira family transcriptional regulator, biotin operon repressor / biotin---[acetyl-coa-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon | Putative pyruvate carboxylase; Carbamoyl-phosphate synthase L chain, N-terminal domain protein | 0.998 |
birA | atuC | DR97_3627 | DR97_5053 | Bira family transcriptional regulator, biotin operon repressor / biotin---[acetyl-coa-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon | annotation not available | 0.520 |
birA | liuB | DR97_3627 | DR97_5834 | Bira family transcriptional regulator, biotin operon repressor / biotin---[acetyl-coa-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon | annotation not available | 0.520 |
birA | liuD | DR97_3627 | DR97_5836 | Bira family transcriptional regulator, biotin operon repressor / biotin---[acetyl-coa-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon | annotation not available | 0.884 |
dhcA | dhcB | DR97_5849 | DR97_5848 | pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit | pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit | 0.999 |
dhcA | liuA | DR97_5849 | DR97_5833 | pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit | Citronelloyl-coa dehydrogenase; Isovaleryl-CoA dehydrogenase 1, mitochondrial; acyl-CoA dehydrogenase, N-terminal domain protein | 0.565 |
dhcA | liuB | DR97_5849 | DR97_5834 | pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit | annotation not available | 0.549 |
dhcA | liuC | DR97_5849 | DR97_5835 | pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit | Enoyl-coa hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family | 0.453 |
dhcA | liuD | DR97_5849 | DR97_5836 | pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit | annotation not available | 0.879 |
dhcA | liuE | DR97_5849 | DR97_5837 | pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit | Hydroxymethylglutaryl-coa lyase; Involved in the L-leucine, isovalerate and acyclic monoterpene catabolism. Catalyzes the cleavage of 3-hydroxy-3- methylglutaryl-CoA (HMG-CoA) to yield acetyl-CoA and acetoacetate. It can also catalyze the cleavage of 3-hydroxy-3-isohexenylglutaryl-CoA (HIHG_CoA) to yield 7-methyl-3-oxooct-6-enoyl-CoA and acetate | 0.954 |
dhcB | dhcA | DR97_5848 | DR97_5849 | pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit | pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit | 0.999 |
dhcB | liuA | DR97_5848 | DR97_5833 | pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit | Citronelloyl-coa dehydrogenase; Isovaleryl-CoA dehydrogenase 1, mitochondrial; acyl-CoA dehydrogenase, N-terminal domain protein | 0.594 |
dhcB | liuB | DR97_5848 | DR97_5834 | pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit | annotation not available | 0.594 |
dhcB | liuC | DR97_5848 | DR97_5835 | pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit | Enoyl-coa hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family | 0.633 |