AcsA protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AcsA

Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase (651 aa)

Predicted Functional Partners:

bdhA

0.950

liuE

0.948

atoB

0.938

fadB

0.937

FadB

0.936

PaaH

0.922

DR97_150

0.918

YfcY

0.918

DR97_3941

0.918

DR97_5617

0.918

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AcsA	DR97_150	DR97_5851	DR97_150	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	0.918
AcsA	DR97_3941	DR97_5851	DR97_3941	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	0.918
AcsA	DR97_5617	DR97_5851	DR97_5617	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	0.918
AcsA	FadB	DR97_5851	DR97_149	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	annotation not available	0.936
AcsA	PaaH	DR97_5851	DR97_261	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	annotation not available	0.922
AcsA	YfcY	DR97_5851	DR97_2130	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	0.918
AcsA	atoB	DR97_5851	DR97_5847	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein; Belongs to the thiolase family	0.938
AcsA	bdhA	DR97_5851	DR97_5845	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	Beta-d-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family	0.950
AcsA	fadB	DR97_5851	DR97_4923	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate	0.937
AcsA	liuE	DR97_5851	DR97_5837	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	Hydroxymethylglutaryl-coa lyase; Involved in the L-leucine, isovalerate and acyclic monoterpene catabolism. Catalyzes the cleavage of 3-hydroxy-3- methylglutaryl-CoA (HMG-CoA) to yield acetyl-CoA and acetoacetate. It can also catalyze the cleavage of 3-hydroxy-3-isohexenylglutaryl-CoA (HIHG_CoA) to yield 7-methyl-3-oxooct-6-enoyl-CoA and acetate	0.948
DR97_150	AcsA	DR97_150	DR97_5851	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	0.918
DR97_150	DR97_3941	DR97_150	DR97_3941	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	0.675
DR97_150	DR97_5617	DR97_150	DR97_5617	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	0.683
DR97_150	FadB	DR97_150	DR97_149	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	annotation not available	0.999
DR97_150	PaaH	DR97_150	DR97_261	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	annotation not available	0.944
DR97_150	YfcY	DR97_150	DR97_2130	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	0.673
DR97_150	atoB	DR97_150	DR97_5847	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	acCoA-C-Actrans: acetyl-CoA C-acetyltransferase family protein; Belongs to the thiolase family	0.652
DR97_150	fadB	DR97_150	DR97_4923	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate	0.991
DR97_150	liuE	DR97_150	DR97_5837	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	Hydroxymethylglutaryl-coa lyase; Involved in the L-leucine, isovalerate and acyclic monoterpene catabolism. Catalyzes the cleavage of 3-hydroxy-3- methylglutaryl-CoA (HMG-CoA) to yield acetyl-CoA and acetoacetate. It can also catalyze the cleavage of 3-hydroxy-3-isohexenylglutaryl-CoA (HIHG_CoA) to yield 7-methyl-3-oxooct-6-enoyl-CoA and acetate	0.915
DR97_3941	AcsA	DR97_3941	DR97_5851	Acetyl-coa c-acetyltransferase family protein; Belongs to the thiolase-like superfamily. Thiolase family	Acetoacetyl-coa synthetase; Acetoacetyl-coenzyme A synthetase; ac_ac_CoA_syn: acetoacetate-CoA ligase	0.918

page 1 of 5

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2022

Credits

Access

Info

About