STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exaBCytochrome c family protein; Is an essential component of the ethanol oxidation system that allows P.aeruginosa to grow on ethanol as the sole carbon and energy source. Is the direct electron acceptor of the quinoprotein ethanol dehydrogenase (QEDH) (145 aa)    
Predicted Functional Partners:
exaA
Alcohol dehydrogenase (cytochrome c); Catalyzes the oxidation of primary alcohols to the corresponding aldehydes, except for methanol, which is a very poor substrate. ExaA is also able to use secondary alcohols as well as amino alcohols like ethanolamine and l-amino-2-propanol, and aldehydes as substrates
 
  
 0.981
pqqB
Pyrroloquinoline quinone biosynthesis protein b; May be involved in the transport of PQQ or its precursor to the periplasm
 
   
 0.965
pqqC
Pyrroloquinoline quinone biosynthesis protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ
 
   
 0.923
pqqE
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ)
 
   
 0.912
cc4
Cytochrome c4 precursor; Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems
     
 0.860
agmR
Bacterial regulatory s, luxr family protein; Positive activator for glycerol metabolism
 
   
 0.845
pqqD
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway
 
   
 0.841
DR97_5874
annotation not available
 
     0.774
DR97_5873
annotation not available
 
     0.773
ercS'
annotation not available
 
     0.757
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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