cirA protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

cirA

annotation not available (653 aa)

Predicted Functional Partners:

DR97_5921

0.975

DR97_5920

0.961

DR97_5922

0.951

fecA

0.909

tonB

0.856

dhbE

0.847

DR97_5924

0.785

pchA

0.759

ybiI

0.719

besA

0.684

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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TSV: tab separated values - can be opened in Excel

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structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_5920	DR97_5921	DR97_5920	DR97_5921	DUF2149 domain-containing protein	Biopolymer transporter ExbD	0.987
DR97_5920	DR97_5922	DR97_5920	DR97_5922	DUF2149 domain-containing protein	annotation not available	0.973
DR97_5920	DR97_5924	DR97_5920	DR97_5924	DUF2149 domain-containing protein	annotation not available	0.642
DR97_5920	cirA	DR97_5920	DR97_5923	DUF2149 domain-containing protein	annotation not available	0.961
DR97_5921	DR97_5920	DR97_5921	DR97_5920	Biopolymer transporter ExbD	DUF2149 domain-containing protein	0.987
DR97_5921	DR97_5922	DR97_5921	DR97_5922	Biopolymer transporter ExbD	annotation not available	0.983
DR97_5921	DR97_5924	DR97_5921	DR97_5924	Biopolymer transporter ExbD	annotation not available	0.772
DR97_5921	cirA	DR97_5921	DR97_5923	Biopolymer transporter ExbD	annotation not available	0.975
DR97_5921	tonB	DR97_5921	DR97_2910	Biopolymer transporter ExbD	Protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	0.642
DR97_5922	DR97_5920	DR97_5922	DR97_5920	annotation not available	DUF2149 domain-containing protein	0.973
DR97_5922	DR97_5921	DR97_5922	DR97_5921	annotation not available	Biopolymer transporter ExbD	0.983
DR97_5922	DR97_5924	DR97_5922	DR97_5924	annotation not available	annotation not available	0.748
DR97_5922	cirA	DR97_5922	DR97_5923	annotation not available	annotation not available	0.951
DR97_5924	DR97_5920	DR97_5924	DR97_5920	annotation not available	DUF2149 domain-containing protein	0.642
DR97_5924	DR97_5921	DR97_5924	DR97_5921	annotation not available	Biopolymer transporter ExbD	0.772
DR97_5924	DR97_5922	DR97_5924	DR97_5922	annotation not available	annotation not available	0.748
DR97_5924	cirA	DR97_5924	DR97_5923	annotation not available	annotation not available	0.785
besA	cirA	DR97_5270	DR97_5923	annotation not available	annotation not available	0.684
besA	dhbE	DR97_5270	DR97_3683	annotation not available	annotation not available	0.734
besA	pchA	DR97_5270	DR97_3680	annotation not available	Isochor_syn- isochorismate synthase family protein	0.650

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