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macB protein (Pseudomonas aeruginosa) - STRING interaction network
"macB" - Macrolide export ATP-binding/permease protein MacB in Pseudomonas aeruginosa
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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macBMacrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides (663 aa)    
Predicted Functional Partners:
PA2389
RND_mfp- efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family (391 aa)
 
 
  0.999
opmQ
Uncharacterized protein; outer_NodT- efflux transporter, outer membrane factor (OMF) lipo, NodT family protein (472 aa)
 
  0.988
tolC_1
type_I_sec_TolC- type I secretion outer membrane , TolC family protein (482 aa)
   
 
  0.964
acrA
Acriflavine resistance protein A; RND_mfp- efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family (354 aa)
 
 
  0.942
rnd
Ribonuclease D; Exonuclease involved in the 3’ processing of various precursor tRNAs. Initiates hydrolysis at the 3’-terminus of an RNA molecule and releases 5’-mononucleotides; Belongs to the RNase D family (374 aa)
         
  0.918
argA
N-Ac-Glu-synth- amino-acid N-acetyltransferase (432 aa)
   
        0.909
emrB
efflux_EmrB- drug resistance MFS transporter, drug-H+ antiporter-2 family protein; Belongs to the major facilitator superfamily (509 aa)
     
 
  0.895
acrD
2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein (1045 aa)
     
 
  0.894
acrB
2A0602- RND transporter, hydrophobe/amphiphile efflux-1 family protein (1043 aa)
     
 
  0.894
lolA
Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (208 aa)
   
   
  0.893
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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