STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pvdQAcyl-homoserine lactone acylase pvdq; Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length). Degrades 3-oxo- C12-HSL, one of the two main AHL signal molecules of P.aeruginosa, and thereby functions as a quorum quencher, inhibiting the las quorum- sensing system. Therefore, may enable P.aeruginosa to modulate its own quorum-sensing-dependent pathogenic potential. Also appears to be required [...] (762 aa)    
Predicted Functional Partners:
DR97_6046
annotation not available
 
   
 0.945
pvdL
Uncharacterized protein; D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1
 
  
 0.941
pvdO
annotation not available
  
  
 0.940
pvdN
annotation not available
  
  
 0.936
pvdR
Membrane fusion protein, macrolide-specific efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
 
  
 0.934
pvdS
Rna polymerase sigma factor, sigma-70 family protein; Belongs to the sigma-70 factor family. ECF subfamily
  
  
 0.887
opmQ
Uncharacterized protein; outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein
  
  
 0.871
PvdF
annotation not available
      
 0.844
PvdI
Peptide synthase; D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1
 
   
 0.777
pvdG
annotation not available
 
  
 0.773
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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