node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CadR | soxR | DR97_4188 | DR97_6160 | cadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator | Merr family transcriptional regulator, redox-sensitive transcriptional activator soxr; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity) | 0.629 |
DR97_2181 | marR | DR97_2181 | DR97_2524 | annotation not available | annotation not available | 0.858 |
DR97_2181 | soxR | DR97_2181 | DR97_6160 | annotation not available | Merr family transcriptional regulator, redox-sensitive transcriptional activator soxr; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity) | 0.847 |
DR97_5267 | NorR | DR97_5267 | DR97_5295 | Putative HTH-type transcriptional regulator; Rrf2_super: Rrf2 family protein | annotation not available | 0.876 |
DR97_5267 | hmp | DR97_5267 | DR97_5296 | Putative HTH-type transcriptional regulator; Rrf2_super: Rrf2 family protein | Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress | 0.942 |
DR97_5267 | iscR | DR97_5267 | DR97_4054 | Putative HTH-type transcriptional regulator; Rrf2_super: Rrf2 family protein | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins | 0.850 |
DR97_5267 | soxR | DR97_5267 | DR97_6160 | Putative HTH-type transcriptional regulator; Rrf2_super: Rrf2 family protein | Merr family transcriptional regulator, redox-sensitive transcriptional activator soxr; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity) | 0.857 |
NorR | DR97_5267 | DR97_5295 | DR97_5267 | annotation not available | Putative HTH-type transcriptional regulator; Rrf2_super: Rrf2 family protein | 0.876 |
NorR | hmp | DR97_5295 | DR97_5296 | annotation not available | Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress | 0.966 |
NorR | iscR | DR97_5295 | DR97_4054 | annotation not available | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins | 0.591 |
NorR | soxR | DR97_5295 | DR97_6160 | annotation not available | Merr family transcriptional regulator, redox-sensitive transcriptional activator soxr; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity) | 0.873 |
hmp | DR97_5267 | DR97_5296 | DR97_5267 | Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress | Putative HTH-type transcriptional regulator; Rrf2_super: Rrf2 family protein | 0.942 |
hmp | NorR | DR97_5296 | DR97_5295 | Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress | annotation not available | 0.966 |
hmp | iscR | DR97_5296 | DR97_4054 | Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins | 0.798 |
hmp | katE | DR97_5296 | DR97_6280 | Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress | Hydroperoxidase ii; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide | 0.503 |
hmp | sodA | DR97_5296 | DR97_1647 | Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress | Superoxide dismutase, fe-mn family; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems | 0.776 |
hmp | soxR | DR97_5296 | DR97_6160 | Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress | Merr family transcriptional regulator, redox-sensitive transcriptional activator soxr; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity) | 0.639 |
iscR | DR97_5267 | DR97_4054 | DR97_5267 | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins | Putative HTH-type transcriptional regulator; Rrf2_super: Rrf2 family protein | 0.850 |
iscR | NorR | DR97_4054 | DR97_5295 | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins | annotation not available | 0.591 |
iscR | hmp | DR97_4054 | DR97_5296 | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins | Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress | 0.798 |