The upcoming version of STRING is available for preview: it includes new data, new enrichment categories (e.g. diseases and tissues) and covers 14000 fully sequenced genomes.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR97_6165
annotation not available (401 aa)
Predicted Functional Partners:
DR97_6163
annotation not available
0.735
DR97_6162
annotation not available
0.592
DR97_3697
annotation not available
0.579
phzB
annotation not available
0.579
DR97_5924
annotation not available
0.467
pbpC
Peptidoglycan D,D-transpeptidase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum
STRING Data Update
